Basic information
- CAS
68399-80-4- Standard SMILES
O=S(=O)(O)CC(O)CN(CCO)CCO- InChIKey
XCBLFURAFHFFJF-UHFFFAOYSA-N- Molecular formula
- C7H17NO6S
- Average molar mass
- 243.28 g/mol
- Monoisotopic mass
- 243.07765844
Names & identifiers
- Preferred name
- 1-Propanesulfonic acid, 3-(bis(2-hydroxyethyl)amino)-2-hydroxy-
- IUPAC
- 3-[bis(2-hydroxyethyl)amino]-2-hydroxypropane-1-sulfonic acid
- English name
- DIPSO
- Molecular formula
- C7H17NO6S
- Molecular weight
- 243.28
Names & synonyms
DIPSONSC 3781451-Propanesulfonic acid, 3-[bis(2-hydroxyethyl)amino]-2-hydroxy-K9ARD8RDK3EINECS 269-992-23-(Bis(2-hydroxyethyl)amino)-2-hydroxypropanesulphonic acid3-(N-Bis(hydroxyethyl)amino)-2-hydroxypropanesulfonic acidN,N-Bis(2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acidNSC-3781451-Propanesulfonic acid, 3-(bis(2-hydroxyethyl)amino)-2-hydroxy-3-[bis(2-hydroxyethyl)amino]-2-hydroxypropanesulphonic acidDTXSID20887355
Show more names
3-(BIS(2-HYDROXYETHYL)AMINO)-2-HYDROXY-1-PROPANESULFONIC ACIDbuffergradeDIPSO bufferDIPSO FREE ACIDDIPSO ULTRAPUREDIPSO SIGMAULTRA3-[bis(2-hydroxyethy
RefChem:436178DTXCID708726551-Propanesulfonic acid, 3-bis(2-hydroxyethyl)amino-2-hydroxy-68399-80-43-(Bis(2-hydroxyethyl)amino)-2-hydroxypropane-1-sulfonic acid3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic Acid3-[bis(2-hydroxyethyl)amino]-2-hydroxypropane-1-sulfonic acidC7H17NO6S
Properties
Computed structural properties
- XLogP
- -5.1
- Topological polar surface area
- 127 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 243
Physicochemical properties
- Melting point
- 189 · 189-192 °C(lit.)
- Density
- 1.494 · 1.494±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 2 O: · H2O: 0.1 M at 20 °C, clear, colorless
- form
- powder to crystal
- color
- White to Almost white
- PH
- 4 · 4.0-5.5 (20℃, 0.1M in H2O)
- pka
- 7.6 · 7.6(at 25℃)
- PH Range
- 7 · 7.0 - 8.2
- Water Solubility
- almost transparency
- BRN
- 2105454 · 2105454
- Major Application
- diagnostic assay manufacturing
- InChI
- InChI=1S/C7H17NO6S/c9-3-1-8(2-4-10)5-7(11)6-15(12,13)14/h7,9-11H,1-6H2,(H,12,13,14)
- InChIKey
- XCBLFURAFHFFJF-UHFFFAOYSA-N
- SMILES
- C(S(O)(=O)=O)C(O)CN(CCO)CCO
- CAS DataBase Reference
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 66.7% (2 of 3) of all reports.
Warning
H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information1-Propanesulfonic acid, 3-bis(2-hydroxyethyl)amino-2-hydroxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesSkin Irrit. 2 (33.3%)
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29221980
- risk_code
- 10-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- F,Xi
- safety_code
- 24/25-36-26-16-7/9
- hazard_class
- IRRITANT
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Uses & manufacturing
General Manufacturing Information1-Propanesulfonic acid, 3-[bis(2-hydroxyethyl)amino]-2-hydroxy-: ACTIVE
Applications
DescriptionDIPSO is a Zwitterionic buffer useful in the pH range of 7.0-8.2. Studies have shown that using one buffer limits the ability to adjust the buffer capacity range. To increase the range of buffer capacity, it is more helpful to combine multiple buffers such as HEPES (sc-29097), MOPS (sc-301170), and DIPSO. This method both expands the pH buffer range and reduces toxicity by reducing the concentration of a single component.
UsesDIPSO, also known as 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid, is a Zwitterionic buffer useful in the pH range of 7.0-8.2.
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖北博杰生物科技有限公司0713-2060728 15629612610 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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