2'-Chloro-2'-deoxyadenosine
Basic information
- CAS
2627-62-5- Standard SMILES
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1Cl- InChIKey
ADXUXRNLBYKGOA-QYYRPYCUSA-N- Molecular formula
- C10H12ClN5O3
- Average molar mass
- 285.69 g/mol
- Monoisotopic mass
- 285.062867
Names & identifiers
- Preferred name
- 2'-Chloro-2'-deoxyadenosine
- IUPAC
- (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol
- English name
- 2'-chloro-2'-deoxyadenosine
- Molecular formula
- C10H12ClN5O3
- Molecular weight
- 285.69
Names & synonyms
2'-Chloro-2'-deoxyadenosine2627-62-52'-Deoxy-2'-chloroadenosineAdenosine, 2'-chloro-2'-deoxy-3MR7O4XF3UDTXSID20180898NSC-289354RefChem:802192'-cdADTXCID60103389(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-chloro-2-(hydroxymethyl)tetrahydrofuran-3-ol(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol
Show more names
2'-chlorodeoxyadenosine(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-olNSC 289354UNII-3MR7O4XF3USCHEMBL600802orb1908675SCHEMBL30504267TNU0306
Database identifiers
- CAS
2627-62-5- PubChem CID
- 100327
- DTXSID
DTXSID20180898- UNII
- 3MR7O4XF3U
- Nikkaji
- J529.759A
Properties
Computed structural properties
- XLogP
- 0.2
- Topological polar surface area
- 119 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 2
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 338
Physicochemical properties
- form
- Solid
- color
- White to off-white
- FDA UNII
- 3 MR7O4XF3U · 3MR7O4XF3U
Chemistry & industry
Applications
Uses2’-Chloro-2’-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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