2-beta-D-ribofuranosyl-4-selenazolecarboxamide
Basic information
- CAS
83705-13-9- Standard SMILES
NC(=O)c1c[se]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1- InChIKey
CKMBACZHCFMPLQ-DBRKOABJSA-N- Molecular formula
- C9H12N2O5Se
- Average molar mass
- 307.17 g/mol
- Monoisotopic mass
- 307.99114
Overview
selenazole analog of tiazofurin
Names & identifiers
- Preferred name
- 2-beta-D-ribofuranosyl-4-selenazolecarboxamide
- IUPAC
- 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-selenazole-4-carboxamide
- English name
- Selenazofurin
- Molecular weight
- 0
Names & synonyms
Selenazofurin83705-13-9CI-9352-beta-D-Ribofuranosyl-4-selenazolecarboxamide4-Selenazolecarboxamide, 2-beta-D-ribofuranosyl-I5R2V02E8ZNSC-3408472 beta-ribofuranosylselenazole-4-carboxamideDTXSID802325692-ribofuranosylselenazole-4-carboxamideRefChem:182272DTXCID60155060
Show more names
SelenazoleCI935CI 935
Selenofurin2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-selenazole-4-carboxamide2-beta-D-Ribofuranosylselenazole-4-CarboxamideNSC 340847BRN 4198668UNII-I5R2V02E8ZNSC3408474-Selenazolecarboxamide, 2-.beta.-D-ribofuranosyl-
Database identifiers
- CAS
83705-13-9- PubChem CID
- 100665
- DTXSID
DTXSID80232569- ChEMBL
CHEMBL3144001- UNII
- I5R2V02E8Z
- Nikkaji
- J55.627K
Properties
Computed structural properties
- Topological polar surface area
- 126 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 305
Physicochemical properties
- FDA UNII
- 5 R2V02E8Z · I5R2V02E8Z
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Applications
UsesSelenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml[1].
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
4 records
Compound notes
Loading…