Basic information
- CAS
23623-06-5- Standard SMILES
COc1ccc(-c2nc3ccc(-c4nc5ccc(N6CCN(C)CC6)cc5[nH]4)cc3[nH]2)cc1- InChIKey
ZEEIKPHYGCYRRH-UHFFFAOYSA-N- Molecular formula
- C26H26N6O
- Average molar mass
- 438.5 g/mol
- Monoisotopic mass
- 438.21680947
Names & identifiers
- Preferred name
- Hoe 32021
- IUPAC
- 2-(4-methoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
- English name
- HOE-32021
- Molecular formula
- C26H26N6O
- Molecular weight
- 438.52
Names & synonyms
HOE 3202123623-06-5DTXSID30435169RefChem:347828DTXCID503859952-(4-methoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazoleHOE-32021CS-1307CHEMBL316907orb1707208SCHEMBL14669391SCHEMBL18007159
Show more names
HOE 32021, >99%2,6'-Bibenzimidazole, 2'-(4-methoxyphenyl)-6-(4-methyl-1-piperazinyl)-2'-(4-methoxy-phenyl)-5-(4-methyl-piperazin-1-yl)-1(3)H,1'(3')H-[2,5']bibenzoimidazolyl
C26H26N6OHOE32021YAA62306MFCD25976732AKOS030526747DA-74242HY-15562MS-27864
Database identifiers
- CAS
23623-06-5- PubChem CID
- 10071840
- DTXSID
DTXSID30435169- ChEMBL
CHEMBL316907- Nikkaji
- J1.367.259H
Properties
Computed structural properties
- XLogP
- 4.3
- Topological polar surface area
- 73.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 649
Physicochemical properties
- Boiling point
- 721.5 · 721.5±70.0 °C(Predicted)
- Density
- 1.294 · 1.294±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 25 ℃: · 25℃: DMSO or water Protect from light
- form
- Powder
- pka
- 10.92 · 10.92±0.10(Predicted)
- color
- Off-white to pink
- Appearance
- Solid Powder
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
DescriptionHOE 32021 is one of Hoechst stains which are Bis-benzimides used as blue fluorescent dyes to stain DNA.
UsesHOE 32021 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Suppliers21 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Aladdin Scientific[email protected]
西安凯新生物科技有限公司029-68881181 13619217766 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
AdooQ BioScience, LLC+1 (866) 930-6790 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
斯派螺（武汉）药物研发有限公司[email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
天津凯利奇生物科技有限公司15076683720 · [email protected]
上海立崎生物医学研究中心18014399201 · [email protected]
爱必信（上海）生物科技有限公司13761418683 · [email protected]
Musechem+1-800-259-7612 · [email protected]
江苏艾康生物医药研发有限公司025-66113011 19370895928 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
烟台盛凯伦化学科技有限公司开发区第一分公司13356901049 · [email protected]
上海皓元医药股份有限公司021-58950125 · [email protected]
上海安能健生物医药科技有限公司021-68781987 13818305065 · [email protected]
上海博拓生物科技有限公司16621358918 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…