Basic information
- CAS
25620-78-4- Standard SMILES
Nc1ccc(C(O)(c2ccc(N)cc2)c2ccc(N)cc2)cc1- InChIKey
KRVRUAYUNOQMOV-UHFFFAOYSA-N- Molecular formula
- C19H19N3O
- Average molar mass
- 305.4 g/mol
- Monoisotopic mass
- 305.15281224
Names & identifiers
- Preferred name
- Tris(p-aminophenyl)methanol
- IUPAC
- tris(4-aminophenyl)methanol
- English name
- CI 42500
- Molecular formula
- C19H19N3O
- Molecular weight
- 305.37
Names & synonyms
Pararosaniline baseTris(4-aminophenyl)methanolTRIS(P-AMINOPHENYL)METHANOLFuchsin dye baseParafuchsin carbinolTris (4-aminophenyl) carbinolMethanol, tris(4-aminophenyl)-4,4',4''-Triaminotrityl alcohol4,4',4''-TriaminotriphenylcarbinolBenzenemethanol, 4-amino-.alpha.,.alpha.-bis(4-aminophenyl)-25620-78-4UNII-5YB58864V4
Show more names
MAGENTA OPARAFUCHSINPARAROSANILINEROSANILINE BASEPay rose anilineBASIC PARAFUCHSINPararosaniline>fuchsindyebase[qr]TIMTEC-BB SBB006507
HSDB 6128EINECS 207-395-05YB58864V4METHANOL, TRIS(P-AMINOPHENYL)-Benzenemethanol, 4-amino-alpha,alpha-bis(4-aminophenyl)-DTXSID7060049TRIS(P-AMINOPHENYL)METHANOL [HSDB]RefChem:192142
Database identifiers
- CAS
25620-78-4、467-62-9- PubChem CID
- 10084
- DTXSID
DTXSID7060049
Properties
Computed structural properties
- XLogP
- 2.2
- Topological polar surface area
- 98.3 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 310
Experimental & physicochemical properties
Chemical ClassesDyes -> Di- and Triaryl Dyes
Endocrine DisruptorsPotential endocrine disrupting compound
Melting PointMelting point with decomposition - 205 °C
Physical DescriptionPowder; [MSDSonline]
Other Experimental Properties
The hydrochloride salt, basic parafuchsine and this cmpd (the free base) are readily converted in aq soln from one to another by the addition of acid or base.
dye content approx 95%
Physicochemical properties
- Melting point
- 205 °C · 205 °C (dec.)(lit.)
- Boiling point
- 598.9 · 598.9±50.0 °C(Predicted)
- Density
- 1.287 · 1.287±0.06 g/cm3(Predicted)
- vapor pressure
- 0 Pa · 0Pa at 25℃
- storage temp.
- Refrigerator, under inert atmosphere
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 4.5% (2 of 44) of reports.
Warning
H351 (95.5%): Suspected of causing cancer [Warning Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 5 notifications to the ECHA C&L Inventory.
Danger
Hazard information
Regulatory InformationREACH registered substance: 4,4',4''-triaminotrityl alcohol (EC: 207-395-0)
Hazards Summary
The term pararosaniline is used ambiguously in literature, sometimes referring to the free base, tris(p-aminophenol) methanol (CAS # 467-62-9), but more frequently referring to the hydrochloride salt (CAS # 569-61-9); Pararosaniline: Lifetime intragastric dosing of hamsters and rats causes rapid weight loss, diarrhea, and shortened lifespan, but no evidence of treatment related lesions or tumors; Mutagenic activity observed in reverse mutation assay on rat urine, but all other studies for mutagenicity negative; Emergency treatment: Methemoglobinemia; [HSDB] See Magenta.
Special ReportsITC/USEPA; Information Review #347 (Revised Draft) Pararosaniline (1984)
TSCA Requirements
TSCA 1982 list of chemicals selected for review by ITC.
Proposed rule requires manufacturers of this chemical to report preliminary assessment information concerned with production, use, and exposure to EPA.
Hazard Classes and Categories
Carc. 2 (95.5%)
Carc. 1B (100%)
Chemistry & industry
Uses & manufacturing
Uses
Pararosaniline: Used as a dye intermediate and as a component of basic fuchsin dye for textiles, leather, and paper; [HSDB]
Component of basic fuchsin, a dye which is used in the coloring of textiles, leather, paper products and china clay products, as a filter dye in photography, as a microbiological stain and as a dye intermediate. /Pararosaniline/
Used in the preparation of organic pigments for printing inks and for the paper printing trade, for high speed photoduplicating and photoimaging systems; in the manufacture of carbon paper; in ink for typewriter ribbons; in jet printing for high speed computer applications; in the coloration of fur, anodized aluminum, glass, waxes, polishes, soaps, plastics, drugs and cosmetics, and in specialty applications such as tinting automobile antifreeze solutions and toilet sanitary preparations /Triphenylmethane/
U.S. Production(1977) 1 to 10 million lb /free base and hydrochloride salt/
Methods of ManufacturingTEN TRIS(P-AMINOPHENYL)CARBONIUM SALTS, INCLUDING TRIS(P-AMINOPHENYL)METHANOL, WERE PREPARED AS WATER SOLUBLE SALTS & WATER INSOLUBLE ETHERS WHICH COULD BE USED FOR THE STERILIZATION OF BLOOD CONTAMINATED BY TRYPANOSOMA CRUZI.
General Manufacturing Information
Benzenemethanol, 4-amino-.alpha.,.alpha.-bis(4-aminophenyl)-: ACTIVE
The literature is frequently ambiguous when referring to pararosaniline; sometimes the term signifies the free base, tris(p-aminophenol) methanol (CAS # 467-62-9) but more often it signifies the hydrochloride salt form of the compound (CAS # 569-61-9)
Applications
UsesPararosaniline Base (cas# 467-62-9) is a useful research chemical. Dyes and metabolites.is used in method for preparing Polyaniline from Polyamino compound and 1,4-Cyclohexanedione derivative.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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