Basic information
- CAS
482-70-2- Standard SMILES
CC1=CC(=O)c2ccc(C)cc2C1=O- InChIKey
YZACZIYTZCJVSN-UHFFFAOYSA-N- Molecular formula
- C12H10O2
- Average molar mass
- 186.21 g/mol
- Monoisotopic mass
- 186.06807956
Overview
Chimaphylin is a member of 1,4-naphthoquinones.
Names & identifiers
- Preferred name
- Chimaphilin
- IUPAC
- 2,7-dimethylnaphthalene-1,4-dione
- English name
- Chimaphilin
- Molecular formula
- C12H10O2
- Molecular weight
- 186.21
Names & synonyms
Chimaphilin482-70-22,7-Dimethyl-1,4-naphthoquinone2,7-dimethylnaphthalene-1,4-dioneDTXSID80197462NSC-400245U8Z086618URefChem:125190DTXCID90119953ChimaphylinChimaphilin (6CI)1, 2,7-dimethyl-
Show more names
7-Dimethyl-11,4-Naphthalenedione, 2,7-dimethyl-
2,7-dimethyl-1,4-naphthalenedioneAC1L2QCIUNII-U8Z086618UYZACZIYTZCJVSN-UHFFFAOYSA-NNSC 400245starbld0009547CHIMAPHILIN [MI]CHEBI:3595
Database identifiers
- CAS
482-70-2- PubChem CID
- 101211
- DTXSID
DTXSID80197462- ChEMBL
CHEMBL495277- ChEBI
CHEBI:3595- UNII
- U8Z086618U
- Nikkaji
- J5.981A
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 34.1 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 314
Physicochemical properties
- Melting point
- 113.5 · 113.5-114.5°; mp 232-233°
- Boiling point
- 346.8 · 346.8±42.0 °C(Predicted)
- Density
- 1.187 · 1.187
- FDA UNII
- 8 Z086618U · U8Z086618U
Chemistry & industry
Applications
UsesChimaphilin is an IGF-1R inhibitor (IC50: 0.086 μM). Chimaphilin has antifungal, antioxidant and anticancer activities. Chimaphilin inhibits the growth of both drug-sensitive and drug-resistant osteosarcoma cell lines. Chimaphilin can induce cancer cell apoptosis. Chimaphilin is a main component of pyrola[1][2].
Suppliers21 total
成都埃法生物科技有限公司028-028-85142057 19983342022 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
云南西力生物技术股份有限公司0871-65217109 · [email protected]
AdooQ BioScience, LLC+1 (866) 930-6790 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
武汉天植生物技术有限公司18607101326 15172504745 · [email protected]
上海萄普生物医药技术有限公司15900573766 18018507602 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
爱必信（上海）生物科技有限公司13761418683 · [email protected]
北京沃凯生物科技有限公司010-62971590 18548936886 · [email protected]
上海博湖生物科技有限公司021-57763112 13585886131 · [email protected]
上海莫奇生物科技有限公司13341702378 · [email protected]
四川百奥克睿生物科技有限公司28-86-28-8543-3893 13260669172 · [email protected]
湖北萃园生物科技有限公司18162795156 18162795156 · [email protected]
上海佰世凯生物科技有限公司021-20908456 · [email protected]
烟台盛凯伦化学科技有限公司开发区第一分公司13356901049 · [email protected]
北京谱析科技有限公司400-808-7372 13161114455 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Additional notes
DefinitionChEBI: Chimaphylin is a member of 1,4-naphthoquinones.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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