(R)-N-(5-Amino-6-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-6-oxohexyl)palmitamide
Basic information
- CAS
441022-64-6- Standard SMILES
CCCCCCCCCCCCCCCC(=O)NCCCC[C@@H](N)C(=O)NCCCNCCCCNCCCN- InChIKey
USNCWPSRPOWEBG-SSEXGKCCSA-N- Molecular formula
- C32H68N6O2
- Average molar mass
- 568.9 g/mol
- Monoisotopic mass
- 568.54037543
Names & identifiers
- Preferred name
- (R)-N-(5-Amino-6-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-6-oxohexyl)palmitamide
- IUPAC
- N-[(5R)-5-amino-6-[3-[4-(3-aminopropylamino)butylamino]propylamino]-6-oxohexyl]hexadecanamide
- English name
- AMXT 1501)
- Molecular formula
- C32H68N6O2
- Molecular weight
- 568.92
Names & synonyms
AMXT-1501441022-64-6(R)-N-(5-Amino-6-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-6-oxohexyl)palmitamideC3ZUM5A33FCHEMBL474635orb1740231SCHEMBL10033832MQT 1501NSC746711NSC-746711HY-124617CS-0087137
Show more names
AMXT 1501)AMXT-1501 (AMXT1501AMXT-1501 tetrahydrochloride (AMXT1501
T69249Hexadecanamide, N-[(5R)-5-amino-6-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-6-oxohexyl]-N-[(5R)-5-Amino-6-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-6-oxohexyl]hexadecanamide
Database identifiers
- CAS
441022-64-6- PubChem CID
- 10144565
- ChEMBL
CHEMBL474635- UNII
- C3ZUM5A33F
Properties
Computed structural properties
- XLogP
- 6
- Topological polar surface area
- 134 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 32
- Heavy atoms
- 40
- Formal charge
- 0
- Complexity
- 549
Physicochemical properties
- Boiling point
- 755.186 · 755.186±60.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 0.958 · 0.958±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- pka
- 15.335 · 15.335±0.46(predicted)
- form
- Solid
- color
- White to off-white
Chemistry & industry
Applications
DescriptionAMXT1501 is a polyamine uptake inhibitor, also inhibiting the putrescine transport in epimastigotes (the insect stage of t. cruzi)
UsesAMXT1501 is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells[1].
Related reactions
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Compound notes
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