Basic information
- CAS
476-69-7- Standard SMILES
COc1cc2c3c(c1O)-c1c(ccc(OC)c1OC)C[C@@H]3N(C)CC2- InChIKey
IDQUPXZJURZAGF-ZDUSSCGKSA-N- Molecular formula
- C20H23NO4
- Average molar mass
- 341.4 g/mol
- Monoisotopic mass
- 341.16270821
Overview
corydine has been reported in Laurelia novae-zelandiae, Stephania tetrandra, and other organisms with data available.
Names & identifiers
- Preferred name
- (+)-Corydine
- IUPAC
- (6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol
- English name
- (+)-CORYDALINE
- Molecular formula
- C20H23NO4
- Molecular weight
- 341.4
Names & synonyms
Corydine476-69-7(+)-CorydineGlaucentrined-CorydineGlaucentrin(S)-(+)-Corydine1O1D15OP5R(6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol(6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinolin-1-olGlaucocerinite 8120RefChem:56426
Show more names
CORYDINE, (+)-O11-Methylcorytuberine2,10,11-trimethoxy-6a-alpha-aporphin-1-o
(6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinoline-1-ol(6aS)-5,6,6a,7-Tetrahydro-2,10,11-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-1-olCHEMBL489524O(sup 11)-Methylcorytuberine4H-Dibenzo(de,g)quinolin-1-ol, 5,6,6a,7-tetrahydro-2,10,11-trimethoxy-6-methyl-, (S)-BRN 0095568UNII-1O1D15OP5RMFCD00076020
Database identifiers
- CAS
476-69-7- PubChem CID
- 10153
- DTXSID
DTXSID00963883- ChEMBL
CHEMBL489524
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 51.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 475
Physicochemical properties
- Melting point
- 165 · 165-167℃
- alpha
- 20 · D20 +204° (c = 1.6 in chloroform)
- Boiling point
- 477.03 °C · 477.03°C (rough estimate)
- Density
- 1.222 · 1.222±0.06 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5614 · 1.5614 (estimate)
- storage temp.
- 4 °C, · 4°C, Inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 9.68 · 9.68±0.20(Predicted)
- color
- White to Off-White
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 1 O1D15OP5R · 1O1D15OP5R
- Toxicity
- 50 subcutaneous · LD50 subcutaneous in mouse: 115mg/kg
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 subcutaneous in mouse: 115mg/kg
Chemistry & industry
Applications
Uses(+)-Corydine is an isoquinoline alkaloid from the tubers of Corydalis cava and has been shown to inhibit acetylcholinesterase in a dose-dependant manner.
Suppliers68 total
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
成都普瑞法科技开发有限公司+86-028-82633397 18982077548 · [email protected]
銘瑞集團有限公司17318633522 · [email protected]
成都乐美天医药科技有限公司17308096051 17308096051 · [email protected]
成都埃法生物科技有限公司028-028-85142057 19983342022 · [email protected]
江苏永健医药科技有限公司17701422015 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
成都市久鼎化学技术有限公司18584079237 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
云南西力生物技术股份有限公司0871-65217109 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
成都普睿法药物研发有限公司82633860 18982077548 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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