Basic information
- CAS
478-84-2- Standard SMILES
CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]c(Br)c(c34)C[C@H]2N(C)C1- InChIKey
VKRAXSZEDRWLAG-SJKOYZFVSA-N- Molecular formula
- C20H24BrN3O
- Average molar mass
- 402.3 g/mol
- Monoisotopic mass
- 401.11027
Names & identifiers
- Preferred name
- Bromolysergide
- IUPAC
- (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
- English name
- 2-bromolysergic acid diethylamide
- Molecular formula
- C20H24BrN3O
- Molecular weight
- 402.33
Names & synonyms
BROMOLYSERGIDE2-Bromo-LSD478-84-2Bromlysergamide2-Bromo-D-lysergic acid diethylamideBrom LSDUSAF SZ-1BOL-1482-Br-LSDD-2-Bromolysergic acid diethylamide2-Brom-D-lysergic acid diethylamineBROMOLYSERGIDE [MI]
Show more names
BOLBromLSDBromo-LSD2-bromo LSD (solution)2-Bromo-LSD 2-Bromo-LSDMethylergometrine Impurity 33
D-2-Brom-diethylamide of lysergic acid(6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamideDTXSID30878496Bromolysergic acid diethylamide2-BROMO-N,N-DIETHYL-D-LYSERGAMIDE2-Bromo-9,10-didehydro-N,N-diethyl-6-methylergoline-8-beta-carboxamide9,10-Didehydro-N,N-diethyl-2-bromo-6-methylergoline-8-beta-carboxamideErgoline-8-beta-carboxamide, 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-
Database identifiers
- CAS
478-84-2- PubChem CID
- 10171
- DTXSID
DTXSID30878496- ChEMBL
CHEMBL274384- UNII
- JUA77QEU32
Properties
Computed structural properties
- XLogP
- 4
- Topological polar surface area
- 39.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 3
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 561
Physicochemical properties
- Melting point
- 120 · 120-127°
- alpha
- 20 · D20 +15° (c = 0.5 in pyridine); D20 +53° (c = 0.5 in chloroform)
- Density
- 1.304 · 1.3040 (rough estimate)
- refractive index
- 1.677 · 1.6770 (estimate)
- solubility
- 10 mg/mlEthanol: · DMSO: Soluble: =10 mg/mlEthanol: Soluble: =10 mg/ml
- form
- Solid
- Boiling point
- 580.7 · 580.7±50.0 °C(Predicted)
- pka
- 15.65 · 15.65±0.40(Predicted)
- color
- Off-white to light yellow
- FDA UNII
- 77 QEU32 · JUA77QEU32
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- 225 · H225-H302+H312+H332-H319
- Precautionary statements
- 210 · P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P321-P330-P362+P364-P337+P313-P370+P378-P403+P235-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS07
- Hazard statements
- H225-H302+H312+H332-H319
- Precautionary statements
- P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P321-P330-P362+P364-P337+P313-P370+P378-P403+P235-P501
Chemistry & industry
Applications
Uses2-Bromo-LSD (BOL-148; Bromolysergide) is a Dopamine Receptor antagonist that directly affects dopamine neurons in the substantia nigra neostriatum. 2-Bromo-LSD increases the hydroxylation of tyrosine in striatum and antagonizes the decrease of Apomorphine-induced DOPA accumulation. 2-Bromo-LSD also blocks the 5-HT Receptor mediated DOPA formation[1].
Suppliers10 total
淄博容纳生物科技有限公司+86-86-13583358881 +8618560316533 · [email protected]
湖北扬信医药科技有限公司0714-3999001 19171453112 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
湖北扬信医药科技有限公司07143299675 13092790750 · [email protected]
河南天孚化工有限公司+86-0371-55170693 +86-19937530512 · [email protected]
深圳利斯康医药科技有限公司+86-755-89396905 +86-15013857715 · [email protected]
上海杰股生物科技有限公司021-51698675 · [email protected]
淄博航宇生物科技发展有限公司+86-0533-2185556 +86-15965530500 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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