Basic information
- CAS
120503-45-9- Standard SMILES
COc1nc(N)nc2c1ncn2[C@H]1CC[C@@H](CO)O1- InChIKey
FJAOCNGVPLTSLD-NKWVEPMBSA-N- Molecular formula
- C11H15N5O3
- Average molar mass
- 265.27 g/mol
- Monoisotopic mass
- 265.11748936
Overview
Metacavir is under investigation in clinical trial NCT02965859 (The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B).
Names & identifiers
- Preferred name
- Metacavir
- IUPAC
- [(2S,5R)-5-(2-amino-6-methoxypurin-9-yl)oxolan-2-yl]methanol
- English name
- Pleconaril
- Molecular formula
- C11H15N5O3
- Molecular weight
- 265.2685
Names & synonyms
Metacavir120503-45-92',3'-Dideoxy-6-O-methylguanosineW5EOS3V193Guanosine, 2',3'-dideoxy-6-O-methyl-((2S,5R)-5-(2-Amino-6-methoxy-purin-9-yl)tetrahydrofuran-2-yl)methanolRefChem:156748(5-(2-amino-6-methoxy-9H-purin-9-yl)-tetrahydrofuran-2-yl)methanolUNII-W5EOS3V193[(2S,5R)-5-(2-amino-6-methoxypurin-9-yl)oxolan-2-yl]methanol((2S,5R)-5-(2-Amino-6-methoxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methanolCHEMBL243716
Show more names
orb1699967SCHEMBL10280202SCHEMBL31554842AKOS040748906HY-116154T280222-amino-9-(2,3-dideoxy-2,3-dihydroarabinofuranosyl)-6-methoxy-9h-purine
Database identifiers
- CAS
120503-45-9- PubChem CID
- 10355487
- ChEMBL
CHEMBL243716- UNII
- W5EOS3V193
- Nikkaji
- J1.708.348A
Properties
Computed structural properties
- XLogP
- 0.2
- Topological polar surface area
- 108 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 3
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 321
Physicochemical properties
- FDA UNII
- 5 EOS3V193 · W5EOS3V193
Chemistry & industry
Applications
UsesMetacavir is an orally active, potent and specific nucleoside reverse transcriptase inhibitor against hepatitis B virus (HBV) with antiviral activity[1].
Suppliers5 total
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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