CAS 104051-69-6 Tosufloxacin hydrochloride (HCID 10433396)

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Basic information

CAS: 104051-69-6
Standard SMILES: Cl.NC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2F)C1
InChIKey: CIHZSSCESOLBRQ-UHFFFAOYSA-N
Molecular formula: C19H16ClF3N4O3
Average molar mass: 440.8 g/mol

Names & identifiers

Preferred name: Tosufloxacin hydrochloride
IUPAC: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;hydrochloride
English name: 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)
Molecular formula: C19H15F3N4O3.ClH
Molecular weight: 440.8

Names & synonyms

Tosufloxacin hydrochloride104051-69-6M1FK9581QZABBOTT-60969RefChem:1100190Tosufloxacin (hydrochloride)7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;hydrochlorideTosufloxacin HClUNII-M1FK9581QZSR-01000763339A 60969CHEMBL542832

Show more names

T-3262 hydrochlorideA-61827 hydrochlorideTosufloxacin hydrochloridel7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid,hydrate,hydrochloride7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophe-nyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)

orb1219161orb1298596SCHEMBL3754459HY-B1802BCIHZSSCESOLBRQ-UHFFFAOYSA-NEEA05169AKOS040759544CCG-220465

Properties

Computed structural properties

Topological polar surface area: 99.8 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 10
Rotatable bonds: 3
Heavy atoms: 30
Formal charge: 0
Complexity: 708

Physicochemical properties

Melting point: 247 · 247-250° (dec)
FDA UNII: 1 FK9581QZ · M1FK9581QZ

Chemistry & industry

Applications

UsesTosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria[1][2].