Basic information
- CAS
86636-92-2- Standard SMILES
C=CC(=O)c1ccc2cc(N(C)C)ccc2c1- InChIKey
HMWAJFNEGAJETK-UHFFFAOYSA-N- Molecular formula
- C15H15NO
- Average molar mass
- 225.28 g/mol
- Monoisotopic mass
- 225.1153641
Names & identifiers
- Preferred name
- Acrylodan
- IUPAC
- 1-[6-(dimethylamino)naphthalen-2-yl]prop-2-en-1-one
- English name
- 6-ACRYLOYL-2-DIMETHYLAMINONAPHTHALENE
- Molecular formula
- C15H15NO
- Molecular weight
- 225.29
Names & synonyms
Acrylodan86636-92-26-Acryloyl-2-dimethylaminonaphthaleneDTXSID802357372-Propen-1-one, 1-(6-(dimethylamino)-2-naphthalenyl)-RefChem:109442DTXCID101582281-(6-(Dimethylamino)naphthalen-2-yl)prop-2-en-1-one1-[6-(dimethylamino)naphthalen-2-yl]prop-2-en-1-oneMFCD004675451-(6-(Dimethylamino)-2-naphthalenyl)-2-propen-1-oneHMWAJFNEGAJETK-UHFFFAOYSA-N
Show more names
1-(6-Dimethylamino-naphthalen-2-yl)-propenoneAcrylodan [6-Acryloyl-2-dimethylaminophthalene]ACRYLODAN [6-ACRYLOYL-2-DIMETHYLAMINONAPHTHALENE]Acrylodan [6-acryloyl-2-dimethylaminonaphthalene] - 5 mg
SCHEMBL300438orb1690200SCHEMBL29728324AKOS016846091CS-W020970HY-W040230AS-77844PD158373
Database identifiers
- CAS
86636-92-2- PubChem CID
- 104901
- DTXSID
DTXSID80235737- Nikkaji
- J624.192A
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 20.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 3
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 297
Physicochemical properties
- Melting point
- 130 · 130-131 °C(Solv: ethanol (64-17-5); water (7732-18-5))
- Boiling point
- 388.3 · 388.3±24.0 °C(Predicted)
- Density
- 1.1 · 1.100±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- form
- Solid
- pka
- 4.32 · 4.32±0.40(Predicted)
- color
- Light yellow to yellow
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety & regulation
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Applications
DescriptionAcrylodan is a sulfhydryl-reactive fluorescent probe for protein structural studies.
UsesAcrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys34[1][2].
Suppliers20 total
北京阿克曼科技有限公司18001219251
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深圳市丽晶生化科技有限公司
Related reactions
1 records
Compound notes
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