2-Chloro-6-(1-piperazinyl)pyrazine

HCID 107992
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Basic information

CAS
64022-27-1
Standard SMILES
Clc1cncc(N2CCNCC2)n1
InChIKey
CJAWPFJGFFNXQI-UHFFFAOYSA-N
Molecular formula
C8H11ClN4
Average molar mass
198.65 g/mol
Monoisotopic mass
198.0672241

Names & identifiers

Preferred name
2-Chloro-6-(1-piperazinyl)pyrazine
IUPAC
2-chloro-6-piperazin-1-ylpyrazine
English name
MK 212 hydrochloride
Molecular formula
C8H11ClN4
Molecular weight
198.65

Names & synonyms

64022-27-1MK-2122-chloro-6-(piperazin-1-yl)pyrazine2-Chloro-6-(1-piperazinyl)pyrazine2-chloro-6-piperazin-1-ylpyrazine6-Chloro-2-(1-piperazinyl)pyrazinePyrazine, 2-chloro-6-(1-piperazinyl)-62C3N7238UNSC-317326MK212 cpdRefChem:541479MK 212
Show more names
MK212HClMK 212 hydrochloride4-(6-Chloro-2-pyrazinyl)piperazinePyrazine,2-chloro-6-(1-piperazinyl)-2-CHLORO-6-(PIPERAZIN-1-YL)PYRAZINE, MK2126-CHLORO-2-(1-PIPERAZINYL)PYRAZINE HYDROCHLORIDE
MFCD04975444CHEMBL269521UNII-62C3N7238UMK-212 free baseTocris-0941Biomol-NT_000130GTPL165SCHEMBL255453

Database identifiers

CAS
64022-27-1
PubChem CID
107992
DTXSID
DTXSID80214007
ChEMBL
CHEMBL269521
ChEBI
CHEBI:92360
UNII
62C3N7238U
Nikkaji
J22.665C

Properties

Computed structural properties

XLogP
0.5
Topological polar surface area
41.1 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
4
Rotatable bonds
1
Heavy atoms
13

Physicochemical properties

storage temp.
Keep in dark place,Inert atmosphere,Room temperature
FDA UNII
62 C3N7238U · 62C3N7238U
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
317 · H317-H319
Precautionary statements
280 · P280-P305+P351+P338

Safety & regulation

Safety data

hs_code
2933998090
Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H317-H319
Precautionary statements
P280-P305+P351+P338

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationEndogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.

Applications

UsesMK 212 Hydrochloride is a 5-HT2C agonist that may possess antipsychotic activity; however, mainly functions as an anti-stress treatment when ingested.

Suppliers31 total

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
太原市瑞和丰科贸有限公司+86 351 7031519 · [email protected]

Additional notes

DefinitionChEBI: 2-chloro-6-(1-piperazinyl)pyrazine is a N-arylpiperazine.

Related reactions

21 records
New reaction record

Compound notes

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