2-Bromoethanol
Completing data — refresh the page later to see the latest
Basic information
- CAS
29155-34-8- Standard SMILES
OCCBr- InChIKey
LDLCZOVUSADOIV-UHFFFAOYSA-N- Molecular formula
- C2H5BrO
- Average molar mass
- 124.96 g/mol
- Monoisotopic mass
- 123.95237688
Overview
2-bromoethanol is a colorless to dark brown liquid. Sweet burning taste. (NTP, 1992)
Names & identifiers
- Preferred name
- 2-Bromoethanol
- IUPAC
- 2-bromoethanol
- English name
- 2-Bromoethanol
- Molecular formula
- C2H5BrO
- Molecular weight
- 124.96
Names & synonyms
2-BROMOETHANOL540-51-2Ethylene bromohydrinEthanol, 2-bromo-BromoethanolGlycol bromohydrin2-Hydroxyethyl bromide1-Bromo-2-ethanolEthylenebromohydrin2-Bromoethyl alcoholNSC-2869Z33995S34R
Show more names
2-BromethanolDKSI056HO-PEG1-BrDKFELEX0079BROMOETHANOL-2
beta-bromoethyl alcoholRefChem:596595208-748-12-bromoethan-1-ol2-Bromo-1-ethanolDTXSID80202002-bromo-ethanolC2H5BrO
Database identifiers
- CAS
29155-34-8、540-51-2- PubChem CID
- 10898
- DTXSID
DTXSID8020200- ChEMBL
CHEMBL468583- UNII
- Z33995S34R
- EC Number
- 208-748-1
- Nikkaji
- J1.597K
Properties
Computed structural propertiesFilling in
- XLogP
- 0.2
- Topological polar surface area
- 20.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 4
- Formal charge
- 0
- Complexity
- 10
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Halogenated Alcohols
SpringerMaterials PropertiesSchoenflies notation
Density
1.7629 at 68 °F (NTP, 1992) - Denser than water; will sink
1.7629 @ 20°C
Solubility10 to 50 mg/mL at 66 °F (NTP, 1992)
Flash Point
105 °F (NTP, 1992)
105 °F
Boiling Point
300 to 302 °F at 750 mmHg (Decomposes) (NTP, 1992)
150 °C @760 [mm Hg]
Vapor Pressure
12 mmHg at 122 °F (NTP, 1992)
2.06 [mmHg]
Physical Description
2-bromoethanol is a colorless to dark brown liquid. Sweet burning taste. (NTP, 1992)
Colorless to dark brown liquid. Sweet burning taste; [CAMEO]
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (95.5%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P262, P264, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 111 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Ethanol, 2-bromo-
Status: Active Update: 10-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23691
2-Bromoethanol: Does not have an individual approval but may be used under an appropriate group standard
DOT LabelFlammable Liquid
Fire HazardsThis compound is combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Vapors cause irritation to eyes and mucous membranes as well as headache, respiratory distress, and loss of consciousness. Ingestion has similar effects plus nausea and vomiting. Contact with the skin may cause severe dermatitis.
Hazards Summary
Highly toxic; [Quick CPC] Corrosive to the skin, eyes, and respiratory tract, it may cause chemical pneumonitis. [CHEMINFO MSDS] A skin and eye irritant and may be corrosive; Inhalation of vapors may cause loss of consciousness and respiratory distress; [CAMEO]
Reactive GroupAlcohols and Polyols
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationEthanol, 2-bromo-: ACTIVE
Applications
Description2-bromoethanol, a halogenated alipathic hydrocarbon, is a widely used industrial chemical. It is also a contaminant in food such as wheat and flour during treatment with ethylene oxide. 2-Bromoethanol was also found as a metabolite of 1,2-dibromoethane. A known carcinogen in experimental animals. 2-Bromoethanol is highly toxic in vivo and is a potent mutagen. Fatty acid conjugates of 2-bromoethanol that have been identified after 2-bromoethanol administration to rats may explain the long term 2-bromoethanol accumulation and retention in body tissues. Chronic exposure to 2-bromoethanol causes liver and kidney toxicity. 2- Bromoethanol also induces extensive lipid peroxidation in rat liver, kidney and testis slices and inhibits liver mitochondria respiration[1].
Uses2-Bromoethanol is used in selective reduction of nitroarenes (PcFe(II)/NaBH4/2-bromoethanol catalyst system). It is not used much forany commercial purpose. The risk of exposure to this compound arises when ethylene oxide reacts with hydrobromic acid. It is used as a solvent and organic synthetic raw material. 2-Bromoethanol finds application in the synthesis of 2-piperidin-1-yl-ethanol by reacting with piperidine.
General DescriptionColorless to dark brown liquid. Sweet burning taste.
Upstream & downstream products
Upstream raw materials
Related reactions
1,428 records
Compound notes
Loading…