Basic information
- CAS
550-83-4- Standard SMILES
CCCOc1cc(N)ccc1C(=O)OCCN(CC)CC.Cl- InChIKey
GITPCGSPKUQZTE-UHFFFAOYSA-N- Molecular formula
- C16H27ClN2O3
- Average molar mass
- 330.8 g/mol
- Monoisotopic mass
- 330.1710204
Overview
Propoxycaine Hydrochloride is the hydrochloride salt form of propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity. Propoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.
Names & identifiers
- Preferred name
- Propoxycaine Hydrochloride
- IUPAC
- 2-(diethylamino)ethyl 4-amino-2-propoxybenzoate;hydrochloride
Names & synonyms
Propoxycaine hydrochloride550-83-4Propoxycaine HClRavocaine hydrochlorideDTXSID6045325NSC-760044Blockain HydrochlorideK490D39G46DTXCID4025325Propoxycaine hydrochloride (USP)Propoxycaine hydrochloride [USP]RefChem:176453
Show more names
Hydrochloride, Propoxycaine208-988-7Propoxycaine (hydrochloride)Propoxycainehydrochloride2-(diethylamino)ethyl 4-amino-2-propoxybenzoate;hydrochloride2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate monohydrochloride2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate hydrochloridePravocaine hydrochloride
Database identifiers
- CAS
550-83-4- PubChem CID
- 11078
- DTXSID
DTXSID6045325- ChEMBL
CHEMBL1769- UNII
- K490D39G46
- EC Number
- 208-988-7
Properties
Computed structural properties
- Topological polar surface area
- 64.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 10
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 295
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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