Basic information
- CAS
584-85-0- Standard SMILES
Cn1cncc1C[C@H](NC(=O)CCN)C(=O)O- InChIKey
MYYIAHXIVFADCU-QMMMGPOBSA-N- Molecular formula
- C10H16N4O3
- Average molar mass
- 240.26 g/mol
- Monoisotopic mass
- 240.12224039
Overview
Anserine is a dipeptide comprising of beta-alanine and 3-methyl-L-histidine units. It has a role as an animal metabolite and a mouse metabolite. It is a beta-alanine derivative and a dipeptide. It is a tautomer of an anserine zwitterion.
Names & identifiers
- Preferred name
- Anserine
- IUPAC
- (2S)-2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid
- English name
- L-Anserine
- Molecular formula
- C10H16N4O3
- Molecular weight
- 240.26
Names & synonyms
L-AnserineANSERINE584-85-0beta-alanyl-3-methyl-L-histidineDTXSID30973950HDQ4N37UGVCHEBI:18323(2S)-2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acidL-Histidine, N-beta-alanyl-3-methyl-(2S)-2-(3-aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acidBalanineBeta Alanyl 3 Methylhistidine
Show more names
AnserinAnserine (8CI)TUNA OLIGOPEPTIDEAnserine (Standard)H-β-Ala-His(3-Me)-OHAnserine, 10 mM in DMSOL-Histidine, β-alanyl-3-methyl-N-?-alanyl-3-methyl-L-histidine
Beta-Alanyl-3-MethylhistidineRefChem:915936DTXCID201401390(2S)-2-(3-azaniumylpropanoylamino)-3-(3-methylimidazol-4-yl)propanoate(2S)-2-((3-Amino-1-Oxopropyl)Amino)-3-(3-Methyl-4-Imidazolyl)Propanoic Acid209-545-0OphidineMFCD11040910
Database identifiers
- CAS
584-85-0
Properties
Computed structural properties
- XLogP
- -4
- Topological polar surface area
- 110 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 285
Experimental & physicochemical properties
Melting Point226 - 228 °C
Physical DescriptionSolid
Collision Cross Section
154.8 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
159.77 Ų [M+Na]+ [CCS Type: DT; Method: stepped-field]
152.32 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
Physicochemical properties
- Melting point
- 268 ℃ · 268℃ (decomposition)
- Boiling point
- 611.3 · 611.3±55.0 °C(Predicted)
- Density
- 1.38 · 1.38±0.1 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C(protect from light)
- solubility
- Methanol (Slightly, Heated), Water (Slightly)
- form
- Solid
- pka
- 3.02 · 3.02±0.10(Predicted)
- color
- White to Off-White
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- hs_code
- 2933299090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Pharmacology
Tissue LocationsBrain
Cellular LocationsCytoplasm
Metabolite Pathwaysbeta-Alanine metabolism
Applications
UsesAnserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
Upstream & downstream products
Upstream raw materials
Suppliers100 total
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
苏州华赛生物工程技术有限公司0512-89581819; 18915732708 · [email protected]
盐城通铭生物科技有限公司15195160625 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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