Naronapride
Basic information
- CAS
860174-12-5- Standard SMILES
COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CCN(CCCCCC(=O)O[C@H]2CN3CCC2CC3)C[C@@H]1OC- InChIKey
VGDDOIZXGFJDRC-VJTSUQJLSA-N- Molecular formula
- C27H41ClN4O5
- Average molar mass
- 537.1 g/mol
- Monoisotopic mass
- 536.2765481
Overview
See also: Naronapride Dihydrochloride (active moiety of).
Names & identifiers
- Preferred name
- Naronapride
- IUPAC
- [(3R)-1-azabicyclo[2.2.2]octan-3-yl] 6-[(3S,4R)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]hexanoate
- English name
- Naronapride
- Molecular formula
- C27H41ClN4O5
- Molecular weight
- 537.09
Names & synonyms
Naronapride860174-12-5ATI-7505ATI7505NaronapridaATI 7505058896B00BnaronapridumRefChem:832074(3R)-1-azabicyclo(2.2.2)octan-3-yl 6-((3S,4R)-4-(4-amino-5-chloro-2-methoxybenzamido)-3-methoxypiperidin-1-yl)hexanoateNaronapride [USAN:INN]UNII-058896B00B
Show more names
1-Piperidinehexanoic acid, 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxy-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (3S,4R)-
[(3R)-1-azabicyclo[2.2.2]octan-3-yl] 6-[(3S,4R)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]hexanoate(3R)-1-azabicyclo(2.2.2)oct-3-yl 6-((3S,4R)-4-((4-amino-5-chloro-2-methoxybenzoyl)amino)-3-methoxy-1-piperidinyl)hexanoate1-Piperidinehexanoic acid, 4-((4-amino-5-chloro-2-methoxybenzoyl)amino)-3-methoxy-, (3R)-1-azabicyclo(2.2.2)oct-3-yl ester, (3S,4R)-Naronapride [USAN]Naronapride free baseNARONAPRIDE [INN]Naronapride (USAN/INN)NARONAPRIDE [WHO-DD]
Database identifiers
- CAS
860174-12-5- PubChem CID
- 11237985
- DTXSID
Properties
Computed structural properties
- XLogP
- 2.8
- Topological polar surface area
- 106 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 12
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 752
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- form
- Solid
- color
- White to light yellow
- FDA UNII
- 58896 B00B · 058896B00B
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationEndogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT4 RECEPTORS.
Applications
UsesNaronapride (ATI-7505) is a potent prokinetic 5-HT4 receptor agonist. Naronapride can be used for gastrointestinal diseases research[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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