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Basic information
- CAS
316371-84-3- Standard SMILES
CN(CCOc1ccc(CC2SC(=O)[N-]C2=O)cc1)c1ccccn1.[K+]- InChIKey
RWOGCLSZSSKLEN-UHFFFAOYSA-M- Molecular formula
- C18H18KN3O3S
- Average molar mass
- 395.525 g/mol
- Monoisotopic mass
- 395.07059412
Names & identifiers
- Preferred name
- Potassium 5-(4-{2-[methyl(2-pyridinyl)amino]ethoxy}benzyl)-2,4-dioxo-1,3-thiazolidin-3-ide
- IUPAC
- Potassium 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-2,4-dioxo-1,3-thiazolidin-3-ide
- English name
- ROSIGLITAZONEPOTASSIUMSALT
- Molecular formula
- C18H19N3O3S.K
- Molecular weight
- 396.53
Names & synonyms
Rosiglitazone (potassium)ROSIGLITAZONEPOTASSIUMSALTLHRPXZBKWPFSIR-UHFFFAOYSA-NRosiglitazone potassium salt, PPARgamma agonistpotassium 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)-2,4-dioxothiazolidin-3-ide
Database identifiers
- CAS
316371-84-3- PubChem CID
- 11463585
- DTXSID
DTXSID00466743- UNII
- 2V3E7D3089
Properties
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 2 · Ethanol:2.0(Max Conc. mg/mL);5.06(Max Conc. mM)H2O:1.0(Max Conc. mg/mL);2.53(Max Conc. mM)
- form
- A crystalline solid
- FDA UNII
- 2 V3E7D3089 · 2V3E7D3089
Chemistry & industry
Applications
UsesRosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone potassium is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone potassium can be used in the research of obesity and diabetes, senescence, ovarian cancer[1][2][4][7].
Suppliers13 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
上海尺水药物研究有限公司[email protected] 13564957716 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
BOC Sciences[email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
Aladdin Scientific[email protected]
Related reactions
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Compound notes
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