Pyrazidole
Basic information
- CAS
16154-78-2- Standard SMILES
Cc1ccc2c(c1)c1c3n2CCNC3CCC1.Cl- InChIKey
LIFOOCLGAAEVIF-UHFFFAOYSA-N- Molecular formula
- C15H19ClN2
- Average molar mass
- 262.78 g/mol
- Monoisotopic mass
- 262.1236763
Names & identifiers
- Preferred name
- Pyrazidole
- IUPAC
- 12-methyl-1,4-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-9(16),10(15),11,13-tetraene;hydrochloride
- English name
- 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole monohydrochloride
- Molecular formula
- C15H19ClN2
- Molecular weight
- 262.77776
Names & synonyms
16154-78-2Pirlindole hydrochloridePyrazidoleQ89W8I397CRefChem:174550240-307-98-methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole hydrochlorideMFCD002203708-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole hydrochloride2,3,3A,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole monohydrochloride12-methyl-1,4-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-9(16),10(15),11,13-tetraene;hydrochloride1H-Pyrazino[3,2,1-jk]carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, hydrochloride (1:1)
Show more names
Pirlindole D3 HydrochloridePirlindole hydrochloride salt1,10-Trimethylene-8-methyltetrahydropyrazino(1,2-A)indole hydrochloride2,3,3A,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1J,K)carbazole hydrochloride1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-A)indole hydrochloride1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino-(1,2-a) indolhydrochloride
2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloridePirlindon [Spanish]PirlindonSMR000513888EINECS 240-307-9UNII-Q89W8I397Cpirlindole HClImplementor (TN)
Database identifiers
- CAS
16154-78-2- PubChem CID
- 115141
- DTXSID
DTXSID001350292- ChEMBL
CHEMBL1470001- UNII
- Q89W8I397C
- EC Number
- 240-307-9
Properties
Computed structural properties
- Topological polar surface area
- 17 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 303
Experimental & physicochemical properties
Solubility>39.4 [ug/mL] (The mean of the results at pH 7.4)
Physicochemical properties
- Melting point
- 260 · 260-264℃
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 89 W8I397C · Q89W8I397C
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)
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