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Basic information
- CAS
20448-79-7- Standard SMILES
NC1(C(=O)O)CC2CCC1C2- InChIKey
MPUVBVXDFRDIPT-UHFFFAOYSA-N- Molecular formula
- C8H13NO2
- Average molar mass
- 155.197 g/mol
- Monoisotopic mass
- 155.09462866
Names & identifiers
- Preferred name
- 2-Aminonorbornane-2-carboxylic acid
- IUPAC
- 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
- English name
- 2-AMINO-2-NORBORNANECARBOXYLIC ACID
- Molecular formula
- C8H13NO2
- Molecular weight
- 155.19
Names & synonyms
BCHLAT1-IN-1B-BchLAT1-IN-1 (BCH)2-AMINO-2-NORBORNANECARBOXYLIC ACID2-Aminonorbornane-2-carboxylic acid2-Amino-2-carboxy-bicyclo-2,2,1-heptane2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid
Database identifiers
- CAS
20448-79-7、39669-35-7- PubChem CID
- 115288
- DTXSID
DTXSID10942624- ChEMBL
CHEMBL2074957- ChEBI
CHEBI:167508- Nikkaji
- J236.628B
Properties
Physicochemical properties
- Melting point
- 300 °C · >300 °C(lit.)
- Boiling point
- 295.5 · 295.5±23.0 °C(Predicted)
- Density
- 1.256 · 1.256±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Aqueous Acid (Slightly)
- form
- Solid
- pka
- 2.58 · 2.58±0.20(Predicted)
- color
- White
- Water Solubility
- 100 mM · Soluble to 100 mM in water
- InChI
- 1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)/t5-,6+,8/m1/s1
- InChIKey
- MPUVBVXDFRDIPT-RSHNMJPRSA-N
- SMILES
- NC1(C[C@@H]2CC[C@H]1C2)C(O)=O
- CAS DataBase Reference
- 20448 · 20448-79-7(CAS DataBase Reference)
- UNSPSC Code
- 12352106 · 12352106
- NACRES
- 26 · NA.26
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280-P301+P312-P302+P352-P305+P351+P338
- WGK Germany
- 3 · 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
General Description2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.
Upstream & downstream products
Downstream products
Suppliers2 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
深圳市创鑫生物科技有限公司13417589054 · [email protected]
Additional notes
DefinitionChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.
Related reactions
3 records
Compound notes
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