Completing data — refresh the page later to see the latest
Basic information
- CAS
187739-60-2- Standard SMILES
NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N.O=C(O)c1cc(=O)[nH]c(=O)[nH]1- InChIKey
MNWOBDDXRRBONM-UHFFFAOYSA-N- Molecular formula
- C22H16Cl3N7O6
- Average molar mass
- 580.76 g/mol
Names & identifiers
- Preferred name
- Carboxyamidotriazole orotate
- English name
- Carboxyamidotriazole orotate
- Molecular formula
- C22H16Cl3N7O6
- Molecular weight
- 580.76
Names & synonyms
CAI OrotateL-651582 OrotateOCSMDRBVJRAMCI-UHFFFAOYSA-NCarboxyamidotriazole orotate5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylateL651582,Inhibitor,toxicity,Calcium Channel,L 651582,Ca2+ channels,Ca channels,leukaemia,inhibit,ovarian,chronic,Carboxyamidotriazole,Carboxyamidotriazole Orotate,CAI,Bcr/Abl,L-651582,cancer,myelogenous
Database identifiers
- CAS
187739-60-2- PubChem CID
- 11599548
- UNII
- 776C212QQH
Properties
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 5 mg/mL · DMSO: 5 mg/mL (8.61 mM)
- form
- Solid
- color
- Light yellow to yellow
- FDA UNII
- 776 C212QQH · 776C212QQH
- NCI Drug Dictionary
- carboxyamidotriazole orotate
Chemistry & industry
Applications
UsesCarboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate shows anti-tumor, anti-inflammatory and antiangiogenic effects[1][2].
Suppliers16 total
Aladdin Scientific[email protected]
InvivoChem中国13549236410 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
上海瀚香生物科技有限公司177-54423994 17754423994 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海碧咸医药科技有限公司13816613772 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
上海珞珐生化科技有限公司021-51111890 15317326293 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…