Basic information
- CAS
139968-49-3- Standard SMILES
N#Cc1ccc(C/C(=N\NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2cccc(C(F)(F)F)c2)cc1- InChIKey
MIFOMMKAVSCNKQ-QNKGDIEWSA-N- Molecular formula
- C24H16F6N4O2
- Average molar mass
- 506.4 g/mol
- Monoisotopic mass
- 506.11774474
Overview
an insecticide
Names & identifiers
- Preferred name
- Metaflumizone
- IUPAC
- 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea
- English name
- (E)-Metaflumizone Standard
- Molecular formula
- C24H16F6N4O2
- Molecular weight
- 506.4
Names & synonyms
Metaflumizone139968-49-371I50E2UDI1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea2-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)-N-(4-(trifluoromethoxy)phenyl)hydrazinecarboxamideBAS-320IDTXSID6040373DTXCID601965141-((E)-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)amino)-3-(4-(trifluoromethoxy)phenyl)ureaPROMERISALVERDE (BASF)SIESTA (BASF)
Show more names
Adrenaline Impurity 59Metaflumizone (E-isomer)(E)-Metaflumizone Standard(E)-Metaflumizone 100 μg/mL in AcetonitrileHydrazinecarboxamide, 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-, (2E)-
RefChem:811194PROMERIS (FORT DODGE)PROMERIS DUO COMPONENT METAFLUMIZONE604-167-6(E)-Metaflumizone852403-68-0Metaflumizone, (E)-COL1OR95DS
Properties
Computed structural properties
- XLogP
- 6.2
- Topological polar surface area
- 86.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 6
- Heavy atoms
- 36
- Formal charge
- 0
- Complexity
- 806
Experimental & physicochemical properties
Pesticides
Insecticides
Active substance -> EU Pesticides database: Not approved
Pesticide (Metaflumizone) -> USDA PDB
Physicochemical properties
- storage temp.
- -20 °C · Amber Vial, -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- FDA UNII
- 1 OR95DS · COL1OR95DS
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
P203, P260, P263, P264, P270, P280, P318, P319, P405, and P501 (click each P-code to see the statement)
Warning
H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
P203, P260, P263, P264, P270, P280, P318, P319, P405, and P501 (click each P-code to see the statement)
Hazard information
Regulatory Information
Commission Regulation (EU) No 188/2011
Metaflumizone is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)
2013/205/EU, Dossier complete, Reg. (EU) 2018/155, Reg. (EU) 2025/1092, Reg. (EU) No 922/2014
Hazard Classes and Categories
Repr. 2 (16.9%)
Reproductive toxicity - category 2
Reproductive toxicity - category 2
Repr. 2
Repr. 2
Toxicology
RAIS Toxicity Values
0.33
OPP
0.04
OPP
EPA Human Health Benchmarks for Pesticides
Metaflumizone
0.33
9300
Females 13-49 yrs
0.04
200
Chemistry & industry
Pharmacology
ATC CodeQP - Antiparasitic products, insecticides and repellents
Applications
Uses(E)-Metaflumizone is used as UV absorber for reducing E/Z isomerization of pesticides.It is the (E) Isomer of Metaflumizone (M225825), which is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a heartworm control treatment.
Suppliers5 total
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
上海泰坦科技股份有限公司13023226327 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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