Basic information
- CAS
820959-17-9- Standard SMILES
CC(=O)NCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)O- InChIKey
ROTFCACGLKOUGI-JYJNAYRXSA-N- Molecular formula
- C20H28N8O7
- Average molar mass
- 492.5 g/mol
- Monoisotopic mass
- 492.20809526
Overview
See also: Acetyl octapeptide-3; acetyl tetrapeptide-5 (component of).
Names & identifiers
- Preferred name
- Acetyl tetrapeptide-5
- IUPAC
- (2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
- English name
- Acetyl Tetrapeptide-5
- Molecular formula
- C20H28N8O7
- Molecular weight
- 492.49
Names & synonyms
Acetyl tetrapeptide-5820959-17-9EyeserylY1DFQ308G8UNII-Y1DFQ308G8DTXSID10231560RefChem:109072DTXCID40154051ACETYL TETRAPEPTIDE-5 [INCI]Ac-Beta-Ala-His-Ser-His-OHN-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidineMFCD30179524
Show more names
tetrapeptideAc-β-Ala-His-Ser-Hiscetyl Tetrapeptide-5Tetrapeptide /EyeserylAc-βAla-His-Ser-His-OHN-Ac-β-Ala-His-Ser-HisEyeseryl WIPO、? Eyeseryl
(3-acetamidopropanoyl)-L-histidyl-L-seryl-L-histidine(2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acidAcetyl TetrapeptideDepuffinC20H28N8O7Ac-betaAla-His-Ser-HisAcetyl Tetrapeptide-5/eyeserylDepuffin/Acetyl Tetrapeptide-5
Database identifiers
- CAS
820959-17-9- PubChem CID
- 11620163
Properties
Computed structural properties
- XLogP
- -3.2
- Topological polar surface area
- 231 Ų
- Hydrogen bond donors
- 8
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 14
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 768
Physicochemical properties
- Boiling point
- 1237.3 · 1237.3±65.0 °C(Predicted)
- Density
- 1.443 · 1.443
- storage temp.
- 2 · 2-8°C
- solubility
- PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- pka
- 2.76 · 2.76±0.10(Predicted)
- color
- White to off-white
- Sequence
- Ac-β-{Ala}-His-Ser-His-OH
- Cosmetics Ingredients Functions
- HUMECTANT
- InChIKey
- RIUMNDWYYDHBFO-UDJPXWLSNA-N
- SMILES
- C(O)(=O)[C@H](CC1N=CN=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1N=CN=C1)NC(=O)CCNC(C)=O |&1:3,13,19,r|
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 1 DFQ308G8 · Y1DFQ308G8
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
UsesAcetyl tetrapeptide-5 is known as eye peptide and eye silk peptide. The molecular weight of acetyltetrapeptide-5 is 492.5 and the amino acid sequence is Ac- βAla-His-Ser-His-OH, the molecular formula is C20H28N8O7. The influence of saccharification in the body and the increase of ocular vascular osmotic pressure will make the eye skin form dark circles and edema. Some studies have proved that acetyltetrapeptide-5 can reduce edema by changing the microcirculation of regional skin and the osmotic pressure of liquid, so as to effectively eliminate edema, eye bags and dark circles.
Suppliers100 total
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
Shochem(Shanghai) Co.,Ltd86-21-50800795 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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