Basic information
- Standard SMILES
Cc1cccc2cccnc12- InChIKey
JRLTTZUODKEYDH-UHFFFAOYSA-N- Molecular formula
- C10H9N
- Average molar mass
- 143.18 g/mol
- Monoisotopic mass
- 143.07349929
Overview
8-methylquinoline appears as yellow liquid or oil. (NTP, 1992)
Names & identifiers
- Preferred name
- 8-Methylquinoline
- IUPAC
- 8-methylquinoline
- English name
- 8-Methylquinoline
- Molecular formula
- C10H9N
- Molecular weight
- 143.19
Names & synonyms
Show more names
Database identifiers
- CAS
611-32-5- PubChem CID
- 11910
- DTXSID
DTXSID8020888- ChEMBL
CHEMBL1702610- ChEBI
CHEBI:48984- UNII
- K97B12J636
- EC Number
- 210-264-0
- Nikkaji
- J841I
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 12.9 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 133
Experimental & physicochemical properties
Physical Description
8-methylquinoline appears as yellow liquid or oil. (NTP, 1992)
Liquid
Physicochemical properties
- Melting point
- -80 °C · -80 °C
- Boiling point
- 245 °C · 245 °C
- Density
- 1.052 g/mL · 1.052 g/mL at 25 °C(lit.)
- refractive index
- 20 · n20/D 1.614(lit.)
- Flash point
- 221 °F · 221 °F
- storage temp.
- Room Temperature
- solubility
- Chloroform, Methanol
- pka
- 5.03 · 5.03±0.17(Predicted)
- form
- Liquid
- color
- Clear yellow
- Specific Gravity
- 1.052 · 1.052
- Water Solubility
- 0.1 · 0.1-0.5 g/100 mL at 17 ºC
- BRN
- 111340 · 111340
- InChI
- 1S/C10H9N/c1-8-4-2-5-9-6-3-7-11-10(8)9/h2-7H,1H3
- InChIKey
- JRLTTZUODKEYDH-UHFFFAOYSA-N
- SMILES
- Cc1cccc2cccnc12
- CAS DataBase Reference
- 611 · 611-32-5(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 97 B12J636 · K97B12J636
- NIST Chemistry Reference
- 8 · Quinoline, 8-methyl-(611-32-5)
- EPA Substance Registry System
- 8 · 8-Methylquinoline (611-32-5)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 501 · P501-P261-P271-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P304+P340+P312-P403+P233-P405
- target organs
- Respiratory system
- PPE
- Eyeshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36 · 36/37/38-68-22
- Safety Statements
- 26 · 26-36-45-36/37/39
- WGK Germany
- 3 · 3
- RTECS
- 562000 · VC0562000
- TSCA
- TSCA listed
- HazardClass
- IRRITANT
- HS Code
- 29334900 · 29334900
- Storage Class
- 10 · 10 - Combustible liquids
- Hazard Classifications
- 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3
Safety & regulation
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Quinoline, 8-methyl-
Quinoline, 8-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Quinoline, 8-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Reactivity Profile
8-METHYLQUINOLINE may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Safety & protection
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Safety data
- PPE
- Eyeshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- VC0562000
- hs_code
- 29334900
- risk_code
- 36/37/38-68-22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi,Xn
- safety_code
- 26-36-45-36/37/39
- hazard_class
- IRRITANT
- Storage Class
- 10 - Combustible liquids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P501-P261-P271-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P304+P340+P312-P403+P233-P405
Chemistry & industry
Uses & manufacturing
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Quinoline, 8-methyl-: ACTIVE
Applications
Uses8-Methylquinoline has been used in preparation of osmium chloridophosphine complexes, as quinoline carbene tautomers.Tumorigenic potential of 8-methylquinoline has been evaluated in newborn CD-1 mice and Sprague-Dawley rats.
Uses8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.
General DescriptionYellow liquid or oil.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
Additional notes
DefinitionChEBI: A methylquinoline carrying a methyl substituent at position 8.
Related reactions
Linked notes
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