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Basic information
- CAS
30021-77-3- Standard SMILES
COc1cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1OC)C(=O)OC3- InChIKey
BJGIWVGXMRUMNA-WBYCZGBQSA-N- Molecular formula
- C27H26O12
- Average molar mass
- 542.493 g/mol
- Monoisotopic mass
- 542.14242627
Names & identifiers
- Preferred name
- Cleistanthin B
- IUPAC
- 9-(2H-1,3-Benzodioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl beta-D-glucopyranoside
- English name
- cleistanthin B
- Molecular formula
- C27H26O12
- Molecular weight
- 542.48814
Names & synonyms
cleistanthin BDiphyllin O-glucosideNaphtho[2,3-c]furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4-(β-D-glucopyranosyloxy)-6,7-dimethoxy-
Database identifiers
- CAS
30021-77-3- PubChem CID
- 119458
- DTXSID
DTXSID501014455- ChEMBL
CHEMBL601587- ChEBI
CHEBI:84407- Nikkaji
- J466.548A
Properties
Physicochemical properties
- Boiling point
- 859.1 · 859.1±65.0 °C(Predicted)
- Density
- 1.542 · 1.542±0.06 g/cm3(Predicted)
- storage temp.
- 4 °C, · 4°C, protect from light
- form
- Solid
- pka
- 12 · 12+-.0.70(Predicted)
- color
- Light yellow to yellow
Chemistry & industry
Applications
UsesCleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 μM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo[1][2][3][4].
Suppliers22 total
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
銘瑞集團有限公司17318633522 · [email protected]
成都乐美天医药科技有限公司17308096051 17308096051 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
成都埃法生物科技有限公司028-028-85142057 19983342022 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
成都普睿法药物研发有限公司82633860 18982077548 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
Aladdin Scientific[email protected]
成都普思生物科技股份有限公司028-85370565-229 18080489829 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Related reactions
0 records
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Compound notes
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