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Basic information
- CAS
33458-93-4- Standard SMILES
CC(C)Oc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1- InChIKey
AQFFXPQJLZFABJ-UHFFFAOYSA-N- Molecular formula
- C17H14O5
- Average molar mass
- 298.294 g/mol
- Monoisotopic mass
- 298.08412355
Names & identifiers
- Preferred name
- 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid
- IUPAC
- 9-Oxo-6-[(propan-2-yl)oxy]-9H-xanthene-2-carboxylic acid
- English name
- 6-Isopropoxy-9-xanthone-2-carboxylic acid
- Molecular formula
- C17H14O5
- Molecular weight
- 298.29
Names & synonyms
6-ISOPROPOXY-9-OXOXANTHENE-2-CARBOXYLIC ACIDAH 6809AH6809AH-6809AH 6809, 10 mM in DMSOAH 6809, EP1 and EP2 antagonist6-Isopropoxy-9-xanthone-2-carboxylic acid6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid6-(1-Methylethoxy)-9-oxo-9H-xanthene-2-carboxylic acid9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-
Database identifiers
- CAS
33458-93-4- PubChem CID
- 119461
- DTXSID
DTXSID80187106- ChEMBL
CHEMBL1317823- ChEBI
CHEBI:95289- UNII
- NU957VN2AW
- Nikkaji
- J134.032H
Properties
Physicochemical properties
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 2.5 mg/mL, · ethanol: 2.5 mg/mL, soluble
- form
- crystalline solid or supercooled liquid
- color
- White
- Stability
- 1 year · Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
- InChI
- 1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
- InChIKey
- AQFFXPQJLZFABJ-UHFFFAOYSA-N
- SMILES
- CC(C)Oc1ccc2c(Oc3ccc(cc3C2=O)C(O)=O)c1
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- WGK Germany
- 3 · 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
DescriptionAH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. AH 6809 blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor. It also blocks the accumulation of Ca2+ in Xenopus oocytes expressing the human EP1 receptor. In the human and guinea pig, the activity profile of AH 6809 is similar to that of SC-19220, but it is somewhat more potent. In the mouse, AH 6809 has the highest affinity for the EP2 receptor, but also acts as a weak ligand at the murine EP1 and DP1 receptors. In whole human platelets, AH 6809 is an effective antagonist of the antiaggregatory actions of PGD2, but not PGI2, with an EC50 of about 5 x 10−5 M.
UsesAH-6809 is a prostaglandin E2 receptor antagonist.
Suppliers36 total
合肥曼奇诺生物医药技术有限公司19719236623 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海冬洋生物科技有限公司0512-13601744364 13601744364 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
江苏艾康生物医药研发有限公司025-5885952 15955137747 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
InvivoChem中国13549236410 · [email protected]
Related reactions
0 records
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Compound notes
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