Basic information
- CAS
142-63-2- Standard SMILES
C1CNCCN1.O.O.O.O.O.O- InChIKey
AVRVZRUEXIEGMP-UHFFFAOYSA-N- Molecular formula
- C4H22N2O6
- Average molar mass
- 194.23 g/mol
- Monoisotopic mass
- 194.14778643
Names & identifiers
- Preferred name
- Piperazine, hexahydrate
- IUPAC
- piperazine;hexahydrate
- English name
- Piperazine hexahydrate
- Molecular formula
- C4H22N2O6
- Molecular weight
- 194.23
Names & synonyms
Piperazine hexahydrate142-63-2ArthriticinePiperazine, hexahydrateVermisolParidP3M07B8U64DTXSID50161918RefChem:174398DTXCID3084409piperazine;hexahydrateMFCD00149389
Show more names
PIPERAZINE HYDRATEarpezineusafa-3803Piperazine PIPERAZINE 6 H2OPIPERAZINE6-HYDRATEPiperazine hexahydra
C4H22N2O6PIPERAZINE (HEXAHYDRATE)Diethylenediamine hexahydrateUSAF A-3803UNII-P3M07B8U64AI3-26675Vermyl (TN)Piperazine hydrate CRS
Database identifiers
- CAS
142-63-2- PubChem CID
- 120181
- DTXSID
DTXSID50161918- UNII
- P3M07B8U64
- EC Number
- 604-300-8
Properties
Computed structural properties
- Topological polar surface area
- 30.1 Ų
- Hydrogen bond donors
- 8
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 0
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 26
Physicochemical properties
- Melting point
- 42 · 42-44 °C(lit.)
- Boiling point
- 145 · 145-156 °C(lit.)
- Density
- 1.2903 · 1.2903 (rough estimate)
- vapor pressure
- 0.8 mm · 0.8 mm Hg ( 20 °C)
- refractive index
- 1.48 · 1.4800 (estimate)
- Flash point
- 190 °F · 190 °F
- storage temp.
- 2 · 2-8°C
- form
- Crystalline Powder or Flakes
- color
- White or transparent
- Water Solubility
- almost transparency
- Merck
- 14 · 14,7464
- BRN
- 4455527 · 4455527
- Exposure limits
- 0.03 ppm · ACGIH: TWA 0.03 ppm
- Major Application
- forensics and toxicologypharmaceutical (small molecule)
- InChI
- 1S/C4H10N2.6H2O/c1-2-6-4-3-5-1;;;;;;/h5-6H,1-4H2;6*1H2
- InChIKey
- AVRVZRUEXIEGMP-UHFFFAOYSA-N
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 2.1% (1 of 48) of reports.
Danger
H314 (95.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H317 (95.8%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H334 (95.8%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]；H361 (91.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P233, P260, P261, P264, P271, P272, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P318, P321, P333+P317, P342+P316, P362+P364, P363, P403, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 48 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 48 reports by companies.；There are 6 notifications provided by 47 of 48 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Regulatory Information
Chemical: Piperazine, hexahydrate
Piperazine, hexahydrate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Piperazine: Human health tier II assessment
Hazard Classes and Categories
Skin Corr. 1B (95.8%)；Skin Sens. 1 (95.8%)；Resp. Sens. 1 (95.8%)；Repr. 2 (91.7%)
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
Applications
UsesAnthelminthic.
UsesPiperazine Hexahydrate can be used as an aqueous adhesive.
General DescriptionPiperazine hexahydrate may be used as a standard for the determination of piperazine in pharmaceutical preparations using colorimetric technique.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
34 records
Compound notes
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