Basic information
- CAS
53053-08-0- Standard SMILES
[N-]=[N+]=Nc1ccc(C(=O)ON2C(=O)CCC2=O)cc1- InChIKey
LWAVGNJLLQSNNN-UHFFFAOYSA-N- Molecular formula
- C11H8N4O4
- Average molar mass
- 260.21 g/mol
- Monoisotopic mass
- 260.05455475
Names & identifiers
- Preferred name
- Hydroxysuccinimidyl-4-azidobenzoate
- IUPAC
- (2,5-dioxopyrrolidin-1-yl) 4-azidobenzoate
- English name
- N-Hydroxysuccinimidyl-4-azidobenzoate
- Molecular formula
- C11H8N4O4
- Molecular weight
- 260.21
Names & synonyms
Show more names
Database identifiers
- CAS
53053-08-0- PubChem CID
- 122153
- DTXSID
DTXSID40201094- UNII
- 8ZXQ80NJ3B
- EC Number
- 892-311-0
- Nikkaji
- J749.962K
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 78 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 434
Physicochemical properties
- Melting point
- 171 · 171-172°C
- storage temp.
- 20 °C · −20°C
- solubility
- 50 mg/mL · chloroform: 50 mg/mL
- form
- powder
- color
- Off-white to yellow
- FDA UNII
- 8 ZXQ80NJ3B · 8ZXQ80NJ3B
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P271-P280
- WGK Germany
- 3 · 3
- HS Code
- 2928009090 · 2928009090
Safety & regulation
GHS classification
GHS Classification
Danger
H241 (50%): Heating may cause a fire or explosion [Danger Self-reactive substances and mixtures; Organic peroxides];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
P210, P234, P235, P240, P260, P261, P264, P264+P265, P270, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P380+P375[+P378], P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Safety data
- wgk
- 3
- hs_code
- 2928009090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P271-P280
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Applications
DescriptionN-Hydroxysuccinimidyl-4-azidobenzoate is an aryl azide-based, amine- and photoreactive crosslinker.
UsesUsed as Photosensitive di-heterofunctional crosslinker.
Suppliers63 total
Related reactions
Compound notes
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