Hydroxysuccinimidyl-4-azidobenzoate

HCID 122153

Basic information

CAS
53053-08-0
Standard SMILES
[N-]=[N+]=Nc1ccc(C(=O)ON2C(=O)CCC2=O)cc1
InChIKey
LWAVGNJLLQSNNN-UHFFFAOYSA-N
Molecular formula
C11H8N4O4
Average molar mass
260.21 g/mol
Monoisotopic mass
260.05455475

Names & identifiers

Preferred name
Hydroxysuccinimidyl-4-azidobenzoate
IUPAC
(2,5-dioxopyrrolidin-1-yl) 4-azidobenzoate
English name
N-Hydroxysuccinimidyl-4-azidobenzoate
Molecular formula
C11H8N4O4
Molecular weight
260.21

Names & synonyms

53053-08-0N-Hydroxysuccinimidyl-4-azidobenzoate4-Azidobenzoyloxysuccinimide4-Azidobenzoic acid N-hydroxysuccinimide esterHSABhydroxysuccinimidyl-4-azidobenzoate8ZXQ80NJ3BHydroxysuccinimidyl-p-azidobenzoateNSC-329704DTXSID40201094SUCCINIMIDYL 4-AZIDOBENZOATERefChem:147282
Show more names
Nsc329704SAB,ClickchemistrySuccinimidyl p-azidobenzoateN-Succinimidyl 4-AzidobenzoateN-Hydroxysuccinimide 4-azidobenzoate
DTXCID40123585892-311-0N3-Ph-NHS ester2,5-DIOXOPYRROLIDIN-1-YL 4-AZIDOBENZOATE(2,5-dioxopyrrolidin-1-yl) 4-azidobenzoateMFCD000549633-hydroxy-2,5-dioxopyrrolidin-1-yl 4-azidobenzoaten-(4-azidobenzoyloxy)succinimide

Database identifiers

CAS
53053-08-0
PubChem CID
122153
DTXSID
DTXSID40201094
UNII
8ZXQ80NJ3B
EC Number
892-311-0
Nikkaji
J749.962K

Properties

Computed structural properties

XLogP
1.8
Topological polar surface area
78 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
6
Rotatable bonds
4
Heavy atoms
19

Physicochemical properties

Melting point
171 · 171-172°C
storage temp.
20 °C · −20°C
solubility
50 mg/mL · chloroform: 50 mg/mL
form
powder
color
Off-white to yellow
FDA UNII
8 ZXQ80NJ3B · 8ZXQ80NJ3B

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H241 (50%): Heating may cause a fire or explosion [Danger Self-reactive substances and mixtures; Organic peroxides];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

P210, P234, P235, P240, P260, P261, P264, P264+P265, P270, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P380+P375[+P378], P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesOrg. Perox. B (50%);Skin Irrit. 2 (100%);Eye Irrit. 2 (100%);STOT SE 3 (100%);STOT RE 1 (100%)

Safety data

wgk
3
hs_code
2928009090
Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H315-H319-H335
Precautionary statements
P261-P271-P280

Chemistry & industry

Pharmacology

MeSH Pharmacological Classification · 2 items

Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.

Applications

DescriptionN-Hydroxysuccinimidyl-4-azidobenzoate is an aryl azide-based, amine- and photoreactive crosslinker.

UsesUsed as Photosensitive di-heterofunctional crosslinker.

Suppliers63 total

郑州阿尔法化工有限公司+86-18530059196 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
武汉布林科技有限公司3456065315 13260619011 · [email protected]

Related reactions

1 records

Compound notes

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