Basic information
- CAS
146669-29-6- Standard SMILES
CC(N)(C(=O)O)c1ccc(C(=O)O)cc1- InChIKey
DNCAZYRLRMTVSF-UHFFFAOYSA-N- Molecular formula
- C10H11NO4
- Average molar mass
- 209.2 g/mol
- Monoisotopic mass
- 209.06880783
Overview
glutamate receptor antagonist
Names & identifiers
- Preferred name
- alpha-Methyl-4-carboxyphenylglycine
- IUPAC
- 4-(1-amino-1-carboxyethyl)benzoic acid
- English name
- (RS)-MCPG
- Molecular formula
- C10H11NO4
- Molecular weight
- 209.2
Names & synonyms
146669-29-6alpha-Mcpgalpha-Methyl-4-carboxyphenylglycinealpha-Methyl-cpglyBenzeneacetic acid, alpha-amino-4-carboxy-alpha-methyl-7HJ67IIE31DTXSID80861398alpha-Amino-4-carboxy-alpha-methylbenzeneacetic acidRefChem:199492DTXCID802098322-Methyl-4-carboxyphenylglycineLY 367385
Show more names
(+/-)MCPG[+/-]-MCPG(RS)-MCPG, 10 mM in DMSOalpha-Amino-4-Carboxy-alphaα-Methyl-4-carboxyphenylglycine(RS)-α-Methyl-4-carboxyphenylglycine(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE(RS)-α-Methyl-4- carboxyphenylglycine
(RS)-MCPG4-(1-amino-1-carboxyethyl)benzoic acid(R,S)-MCPGRS-MCPG(+/-)-alpha-Methyl-4-carboxyphenylglycine(+/-)-alpha-Methyl-(4-carboxyphenyl)glycineCHEMBL299683UNII-7HJ67IIE31
Database identifiers
- CAS
146669-29-6
Properties
Computed structural properties
- XLogP
- -2
- Topological polar surface area
- 101 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 271
Physicochemical properties
- Boiling point
- 425.3 · 425.3±40.0 °C(Predicted)
- Density
- 1.39 · 1.390±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- 6 mg/mL · DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming)
- form
- Powder
- pka
- 1.76 · 1.76±0.10(Predicted)
- color
- White
- InChI
- 1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)
- InChIKey
- DNCAZYRLRMTVSF-UHFFFAOYSA-N
- SMILES
- CC(N)(C(O)=O)c1ccc(cc1)C(O)=O
- CAS DataBase Reference
- 146669 · 146669-29-6(CAS DataBase Reference)
- FDA UNII
- 7 HJ67IIE31 · 7HJ67IIE31
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 7 · GHS07
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationDrugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
Applications
Uses(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist.
Suppliers41 total
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
InvivoChem中国13549236410 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
南京诺利斯医药科技有限公司13901585132 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
Ascent Scientific4401179829988 · [email protected]
ChemeGen 中国18818260767 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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