Basic information
- CAS
17079-18-4- Standard SMILES
O=C(O)C1CCCNC1C(=O)O- InChIKey
PTLWNCBCBZZBJI-UHFFFAOYSA-N- Molecular formula
- C7H11NO4
- Average molar mass
- 173.17 g/mol
Overview
effective antagonist at all three types of excitatory amino acid receptors; does not depress responses to acetylcholine or substance P
Names & identifiers
- Preferred name
- 2,3-Piperidinedicarboxylic acid
- IUPAC
- piperidine-2,3-dicarboxylic acid
- English name
- Piperidine-2,3-Dicarboxylic Acid
- Molecular formula
- C7H11NO4
- Molecular weight
- 173.17
Names & synonyms
17079-18-42,3-Piperidinedicarboxylic acidRefChem:81935605-587-2Piperidine-2,3-dicarboxylic acid2,3-Piperidine dicarboxylic acidMFCD0903295946026-75-92,3-Piperidine dicarboxylate2,3-Piperidinedicarboxylic acid, cis-2,3-piperidine dicarboxylic2,3-Piperidinedicarboxylic acid, (2R,3S)-rel-
Show more names
SCHEMBL730490orb1306608SCHEMBL6866874PTLWNCBCBZZBJI-UHFFFAOYSA-Ncis-2,3-piperidine-dicarboxylic acidAKOS015897803PB42859SB34208
Database identifiers
- CAS
17079-18-4、46026-75-9- PubChem CID
- 1226
- EC Number
- 605-587-2
Properties
Computed structural properties
- XLogP
- -2.8
- Topological polar surface area
- 86.6 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 204
Physicochemical properties
- Boiling point
- 419.4 · 419.4±45.0 °C(Predicted)
- Density
- 1.363 · 1.363±0.06 g/cm3(Predicted)
- pka
- 2.08 · 2.08±0.40(Predicted)
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used to prevent SEIZURES or reduce their severity.
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
Applications
Uses2,3-Piperidinedicarboxylic Acid acts as an antagonist of excitatory amino acids in the hippocampus. It is also reported that 2,3-Piperidinedicarboxylic Acid is shown to be neurotoxic and produce highly significant alterations in the physical state of membrane proteins.
Suppliers6 total
海济医药科技（苏州）有限公司18012778619 · [email protected]
扬州瑞宏生物科技有限公司0514-015380367604 15380367604 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]
Richest Group Ltd18017061086 · [email protected]
北京新研汇医药研发有限公司13969155946 · [email protected]
Related reactions
1 records
Compound notes
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