Ethoxyacetic acid

HCID 12301

Basic information

CAS
627-03-2
Standard SMILES
CCOCC(=O)O
InChIKey
YZGQDNOIGFBYKF-UHFFFAOYSA-N
Molecular formula
C4H8O3
Average molar mass
104.1 g/mol
Monoisotopic mass
104.04734412

Overview

Ethoxyacetic acid is a liquid. (NTP, 1992)

Names & identifiers

Preferred name
Ethoxyacetic acid
IUPAC
2-ethoxyacetic acid
English name
Ethoxyacetic acid
Molecular formula
C4H8O3
Molecular weight
104.1

Names & synonyms

ETHOXYACETIC ACID2-Ethoxyacetic acid627-03-2Ethoxy acetic acidAcetic acid, 2-ethoxy-DTXSID7031294467VW095BXNSC-6750DTXCID5011294RefChem:138423210-978-2Acetic acid, ethoxy-
Show more names
Ethoxyacetic2-ethoxyacetateethoxy-aceticaciEthylglycolicacidEthoxyethanoicacidAceticacid,ethoxy-2-ethoxyaceticacidethyloglycolic acid
O-Ethylglycolic acidethoxy-acetic acidMFCD000043102-ethoxy-acetic acidCAS-627-03-2CCRIS 7194NSC 6750EINECS 210-978-2

Database identifiers

CAS
627-03-2
PubChem CID
12301
DTXSID
DTXSID7031294
ChEMBL
CHEMBL1159929
ChEBI
CHEBI:173365
UNII
467VW095BX
EC Number
210-978-2
Nikkaji
J1.694B

Properties

Computed structural properties

XLogP
0
Topological polar surface area
46.5 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
3
Heavy atoms
7

Experimental & physicochemical properties

Chemical ClassesOther Classes -> Other Organic Compounds
SpringerMaterials PropertiesBoiling point
Density1.1021 at 68 °F (NTP, 1992) - Denser than water; will sink
SolubilitySoluble (NTP, 1992)
Flash Point208 °F (NTP, 1992)
Boiling Point403 to 405 °F at 760 mmHg (NTP, 1992)

Physicochemical properties

Boiling point
97 · 97-100 °C/11 mmHg (lit.)
Density
1.102 g/mL · 1.102 g/mL at 25 °C (lit.)
refractive index
20 · n20/D 1.419(lit.)
Flash point
208 °F · 208 °F
storage temp.
2 · 2-8°C
solubility
Chloroform (Slightly), Methanol (Slightly)

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (65.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 73 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

Chemical: Acetic acid, ethoxy-

Ethoxyacetic acid: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
DOT LabelCorrosive
Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: This compound is corrosive. (NTP, 1992)
Hazards SummaryCorrosive to skin and eyes; [eChemPortal: ERMA] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Safety data

PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk
3
tsca
TSCA listed
rtecs
AH3600000
ridadr
UN 3265 8/PG 2
hs_code
29189900

Chemistry & industry

Pharmacology

Cellular LocationsCytoplasm

Uses & manufacturing

General Manufacturing InformationAcetic acid, 2-ethoxy-: ACTIVE
Applications · 2 items

UsesEthoxyacetic acid is used to evaluate toxicity in embryonic stem cell test in mice. It finds application as a biomarker of exposure to alkyl-substituted ethylene glycols and other aliphatic ethers. It is used as a precursor to prepare ethoxy-acetic acid ethoxymethyl ester.

General DescriptionLiquid.

Suppliers100 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]

Additional notes

DefinitionChEBI: Ethoxyacetic acid is a carboxylic acid.

Related reactions

118 records

Compound notes

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