Basic information
- CAS
627-42-9- Standard SMILES
COCCCl- InChIKey
XTIGGAHUZJWQMD-UHFFFAOYSA-N- Molecular formula
- C3H7ClO
- Average molar mass
- 94.54 g/mol
- Monoisotopic mass
- 94.01854252
Names & identifiers
- Preferred name
- 2-Chloroethyl methyl ether
- IUPAC
- 1-chloro-2-methoxyethane
- English name
- 2-Methoxyethyl chloride
- Molecular formula
- C3H7ClO
- Molecular weight
- 94.54
Names & synonyms
2-Chloroethyl methyl ether627-42-91-Chloro-2-methoxyethane2-Methoxyethyl chlorideEthane, 1-chloro-2-methoxy-1-chloro-2-methoxy-ethanemethyl 2-chloroethyl etherEther, 2-chloroethyl methylMFCD00000972methoxyethyl chloride2-MethoxyethylchlorideChloroethyl-methyl ether
Show more names
2-chloroMethyl ethyl etherJACS-627-42-92-Methoxyethyl chlor2-Methoxyethylchlorid2-Chlorethylmethylether
U890TJ10YMChloro-2-methoxyethane2-Chloroethylmethylether2-chloroethylmethyl etherUNII-U890TJ10YMEthane, 1-chloro-2-methoxyHSDB 2722BETA-CHLOROETHYL METHYL ETHER
Database identifiers
- CAS
627-42-9- PubChem CID
- 12316
- DTXSID
DTXSID6060840- UNII
- U890TJ10YM
- EC Number
- 210-999-7
- Nikkaji
- J516I
Properties
Computed structural properties
- XLogP
- 0.7
- Topological polar surface area
- 9.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 2
- Heavy atoms
- 5
- Formal charge
- 0
- Complexity
- 16.4
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Halogenated Ethers
SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy
Density1.0345 @ 20 °C/4 °C
SolubilitySOL IN WATER; VERY SOL IN ETHER
Boiling Point92-93 °C
Refractive IndexINDEX OF REFRACTION: 1.411 @ 20 °C/D
Physical DescriptionLiquid; [MSDSonline]
Physicochemical properties
- Melting point
- -55 °C · -55 °C
- Boiling point
- 89 · 89-90 °C (lit.)
- Density
- 1.035 g/mL · 1.035 g/mL at 25 °C (lit.)
- refractive index
- 20 · n20/D 1.408(lit.)
Safety & regulation
GHS classification
GHS Classification
Danger
H225 (67.3%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P316, P317, P321, P330, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 113 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Ethane, 1-chloro-2-methoxy-
2-Methoxyethyl chloride: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryNearest congener that has been studied is dichloroethyl ether; [HSDB] An irritant; Harmful by inhalation and ingestion; [MSDSonline] See Dichloroethyl ether.
Hazard Classes and CategoriesFlam. Liq. 2 (67.3%)
Toxicology
Environmental Water Concentrations
EXAMINES THE EXPOSURE OF MAN TO ORGANIC COMPDS VIA DRINKING WATER.
THIS COMPOUND HAS BEEN DETECTED IN FINISHED DRINKING WATER.
Safety data
- F
- 9
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 3271 3/PG 2
Chemistry & industry
Uses & manufacturing
General Manufacturing Information
Ethane, 1-chloro-2-methoxy-: ACTIVE
NEAREST CONGENER THAT HAS BEEN STUDIED IS BIS(2-CHLOROETHYL)ETHER. FURTHER GENERAL INFORMATION ON HALOETHERS IN: HUMAN HEALTH EFFECTS, HALOETHERS; USEPA, SD LEE, PHD, PROJECT MANAGER.
Applications
Uses2-Chloroethyl Methyl Ether is used as a reagent in the synthesis of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.
Uses2-Chloroethyl methyl ether was used in the synthesis of acyclic nucleosides of thieno[2,3-d] pyrimidine derivatives.
Uses2-Chloroethyl methyl ether (2-Methoxyethyl chloride) was used in the synthesis of acyclic nucleosides of thieno[2,3-d]pyrimidine derivatives.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
188 records
Compound notes
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