HuagongsheHuagongshe Chemistry Print Report · For research reference only
18-Oxocortisol
18-Oxocortisol · (11b)-11,17,21-trihydroxy-3,20-dioxo-Pregn-4-en-18-al · Pregn-4-en-18-al, 11,17,21-trihydroxy-3,20-dioxo-, (11β)-
Identifiers & Physical Properties
| CAS No. | 2410-60-8 |
|---|---|
| Molecular formula | C21H28O6 |
| Average molar mass | 376.449 g/mol |
| Monoisotopic mass | 376.18858862 g/mol |
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C=O)[C@H]1CC[C@]2(O)C(=O)CO |
| InChIKey | XUQWWIFROYJHCU-UKSDXMLSSA-N |
| PubChem CID | 123712 |
| DTXSID | DTXSID001317244 |
Chemical & Physical Properties
| Melting point | 208.5-209.5 °C |
|---|---|
| Boiling point | 606.4±55.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Storage conditions | Refrigerator |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| Physical state | Solid |
| pKa (acidity coefficient) | 11.85±0.70(Predicted) |
| Color | White to Off-White |
Applications & Uses
Uses
18-Oxocortisol is used in biological studies on anti-malarial drug artesunate restoring metabolic changes in experimental allergic astham.