HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-mercaptomethyl-3-guanidinoethylthiopropionic acid
2-mercaptomethyl-3-guanidinoethylthiopropionic acid · Propanoic acid, 3-[[2-[(aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)-
Identifiers & Physical Properties
| CAS No. | 77102-28-4 |
|---|---|
| Molecular formula | C7H15N3O2S2 |
| Average molar mass | 237.34 g/mol |
| SMILES | NC(N)=NCCSCC(CS)C(=O)O |
| InChIKey | AKPKWZRKZOAAAZ-UHFFFAOYSA-N |
| PubChem CID | 123726 |
Chemical & Physical Properties
| Boiling point | 427.0±55.0 °C(Predicted) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| Solubility | DMSO (Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly, Sonicated) |
| pKa (acidity coefficient) | 3.97±0.11(Predicted) |
| Physical state | Solid |
| Color | White to Off-White |
| Stability | Air Sensitive, Hygroscopic |
| FDA UNII | X8EOD1X17Q |
Applications & Uses
Uses
Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.