HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-(((Diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid
NO-711 · NNC 711 · NNC711,HCl · NNC 05-711 · NO-711 HYDROCHLORIDE · NNC-711 hydrochloride · NNC 711, GAT-1 inhibitor · YZYRTEYMUTWJPL-UHFFFAOYSA-N
Identifiers & Physical Properties
| CAS No. | 145645-62-1 |
|---|---|
| Molecular formula | C21H23ClN2O3 |
| Average molar mass | 386.879 g/mol |
| Monoisotopic mass | 386.13972028 g/mol |
| SMILES | Cl.O=C(O)C1=CCCN(CCON=C(c2ccccc2)c2ccccc2)C1 |
| InChIKey | YZYRTEYMUTWJPL-UHFFFAOYSA-N |
| PubChem CID | 123738 |
| ChEMBL | CHEMBL545050 |
| DTXSID | DTXSID20163126 |
Chemical & Physical Properties
| Storage conditions | protect from light |
|---|---|
| Solubility | H2O: ≥10 mg/mL at 60 °CH2O: 10mg/mL at60°C |
| Physical state | solid |
| Color | off-white |
| InChI | 1S/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-12H,7,13-16H2,(H,24,25) |
| InChIKey | YZYRTEYMUTWJPL-UHFFFAOYSA-N |
| SMILES | Cl[H].OC(=O)C1=CCCN(CCO\N=C(/c2ccccc2)c3ccccc3)C1 |
| FDA UNII | 500M0G931K |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Water hazard class (WGK) | 3 |
| Storage class | 11 - Combustible Solids |
Applications & Uses
Uses
NNC 711 is an anticonvulsant agent and a selective GABA uptake inhibitor (1,2).
Uses
NO-711 hydrochloride is suitable for use as γ-aminobutyric acid (GABA) transporter-1 (GAT-1) antagonists or GABA uptake inhibitor.