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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 123742Generated: October 26, 2026

SQ 28603

603 · SQ28 · SQ 28603 · Squibb 28603 · SQ28603,SQ-28603 · 3-[(2-benzyl-3-sulfanylpropanoyl)amino]propanoic acid · N-[2-(Mercaptomethyl)-1-oxo-3-phenylpropyl]-β-alanine · β-Alanine, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-

https://huagongshe.com/en/chemical/123742

SQ 28603 molecular structure

Identifiers & Physical Properties

CAS No.100845-83-8
Molecular formulaC13H17NO3S
Average molar mass267.35 g/mol
SMILESO=C(O)CCNC(=O)C(CS)Cc1ccccc1
InChIKeyZCTDTVUDURCGFX-UHFFFAOYSA-N
PubChem CID123742
ChEMBLCHEMBL196902
DTXSIDDTXSID60905805

Chemical & Physical Properties

XLogP1.3
Topological polar surface area67.4
Hydrogen bond donors3
Hydrogen bond acceptors4
Rotatable bonds7
Heavy atoms18
Formal charge0
Complexity277
Boiling point533.3±50.0 °C(Predicted)
Density1.216±0.06 g/cm3(Predicted)
Storage conditionsStore at -20°C
SolubilitySoluble in DMSO
pKa (acidity coefficient)4.32±0.10(Predicted)

Applications & Uses

Uses

SQ28603 is a potent and selective inhibitor of neutral endopeptidase 3.4.24.11 (NEP), an enzyme that degrades atrial natriuretic peptide (ANP).