HuagongsheHuagongshe Chemistry Print Report · For research reference only
Corticotropin (4-10)
n-acetyl semax amidate · n-acetyl semax · Ac-Met-Glu-His-Phe-Pro-Gly-Pro · MEHFRWG · ACTH (4-10) · a-MSH (4-10) · ACTH (4-10) a · ACTH (4-10), HUMAN
Identifiers & Physical Properties
| CAS No. | 4037-01-8 |
|---|---|
| Molecular formula | C44H59N13O10S |
| Average molar mass | 962.1 g/mol |
| Monoisotopic mass | 961.4228563 g/mol |
| SMILES | CSCC[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O |
| InChIKey | HAAUASBAIUJHAN-LXOXETEGSA-N |
| PubChem CID | 123787 |
| ChEMBL | CHEMBL2028951 |
| DTXSID | DTXSID001031210 |
Chemical & Physical Properties
| XLogP | -2.9 |
|---|---|
| Topological polar surface area | 409 |
| Hydrogen bond donors | 13 |
| Hydrogen bond acceptors | 14 |
| Rotatable bonds | 29 |
| Heavy atoms | 68 |
| Formal charge | 0 |
| Complexity | 1,740 |
| Density | 1.48±0.1 g/cm3(Predicted) |
| RTECS number | MC0596950 |
| Storage conditions | −20°C |
| pKa (acidity coefficient) | 3.32±0.10(Predicted) |
| Physical state | Solid |
| Color | White to off-white |
| Sequence | Met-Glu-His-Phe-Arg-Trp-Gly |
| InChIKey | HAAUASBAIUJHAN-LXOXETEGSA-N |
| SMILES | C(C1=CNC2=CC=CC=C12)[C@@H](C(=O)NCC(=O)O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCSC)CC1NC=NC=1)CC1C=CC=CC=1 |
| FDA UNII | J48AU3I790 |
| Water hazard class (WGK) | 3 |
Safety & Regulations
| Water hazard class (WGK) | 3 |
|---|
Applications & Uses
Uses
Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.