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Basic information
- CAS
127060-75-7- Standard SMILES
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCNC(=O)[C@H](CCCN=C(N)N)NC(=O)OCc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccnc1)C(=O)O- InChIKey
UXGNARZDONUMMK-LRMQDCNJSA-N- Molecular formula
- C52H69N13O11
- Average molar mass
- 1,052.204 g/mol
- Monoisotopic mass
- 1,051.52395003
Names & identifiers
- Preferred name
- Cgp 42112A
- IUPAC
- N~6~-{N~2~-[(Benzyloxy)carbonyl]-N~5~-(diaminomethylidene)-L-ornithyl}-N~2~-[N-(pyridine-3-carbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-L-isoleucine
- English name
- CGP 42112
- Molecular formula
- C52H69N13O11
- Molecular weight
- 1052.19
Names & synonyms
CGP 42112CGP-42112ACGP 42112 TFACGP42112A, CGP42112CGP-42112 (CGP42112ANGIOTENSIN II ANTAGONISTANGIOTENSIN II RECEPTOR LIGANDNIC-TYR-LYS(Z-ARG)-HIS-PRO-ILECGP 42112, AT2 receptor ligandCGP-42112A >=95%, synthetic, solid
Database identifiers
- CAS
127060-75-7- PubChem CID
- 123794
- DTXSID
DTXSID90155396- ChEMBL
CHEMBL1885579- ChEBI
CHEBI:147302- UNII
- 9Q3V7W3XDD
- Nikkaji
- J343.934H
Properties
Physicochemical properties
- Density
- 1.39 · 1.39±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- 350 · DMSO:350.0(Max Conc. mg/mL);332.64(Max Conc. mM)
- pka
- 3.72 · 3.72±0.22(Predicted)
- form
- solid
- color
- white
- biological source
- synthetic
- Water Solubility
- 1 mg/ml · Soluble to 1 mg/ml in water
- BRN
- 8184948 · 8184948
- InChIKey
- UXGNARZDONUMMK-LRMQDCNJSA-N
- SMILES
- CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCCNC(=O)[C@H](CCCNC(N)=N)NC(=O)OCc3ccccc3)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)c5cccnc5)C(O)=O
- FDA UNII
- 9 Q3V7W3XDD · 9Q3V7W3XDD
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- Safety Statements
- 22 · 22-24/25
- WGK Germany
- 3 · 3
- F
- 10 · 10
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 10
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- safety_code
- 22-24/25
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesCGP-42112A has been used:in the isolation of RNA from fibroblast-like synoviocytes from rheumatoid arthritis patients (RA-FLS)to study its effects on the ERK2 phosphorylation in the cardiomyoblast cell lineas a stimulator of angiotensin II type 2 (AT2) receptor to study its effects on human regional hemodynamic responses mediated by AT2 receptors
Suppliers57 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
Aladdin Scientific[email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
InvivoChem中国13549236410 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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