L-Tyrosine, 3-hydroxy-, mixt. with serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
Basic information
- CAS
37270-69-2- Standard SMILES
NC(CO)C(=O)NNCc1ccc(O)c(O)c1O.N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O- InChIKey
QFLMOYQNYBDXMT-ZCMDIHMWSA-N- Molecular formula
- C19H26N4O9
- Average molar mass
- 454.4 g/mol
- Monoisotopic mass
- 454.16997842
Names & identifiers
- Preferred name
- L-Tyrosine, 3-hydroxy-, mixt. with serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
- IUPAC
- (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid;2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
- English name
- madopar
- Molecular formula
- C10H15N3O5.C9H11NO4
- Molecular weight
- 454.43
Names & synonyms
37270-69-2RefChem:1088294L-Tyrosine, 3-hydroxy-, mixt. with serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazideModoparRo 8-0576LevoparRo 8-0576-7Co-beneldopaLevobens-TevaRo 8-0576-12benserazide, levodopa drug combinationSCHEMBL1134100
Show more names
madopar
DTXSID80958414L-Tyrosine, 3-hydroxy-, mixt. with DL-serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide3-Hydroxy-L-tyrosine--2-amino-3-hydroxy-N-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazonic acid (1/1)3-Hydroxytyrosine--2-amino-3-hydroxy-N-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazonic acid (1/1)
Database identifiers
- CAS
37270-69-2- PubChem CID
- 123809
- DTXSID
DTXSID80958414
Properties
Computed structural properties
- Topological polar surface area
- 252 Ų
- Hydrogen bond donors
- 11
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 8
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 487
Physicochemical properties
- Protein binding
- 0 · Benserazide: 0, Levodopa: 10-30%
- Excreted unchanged in urine
- 0 · Benserazide: 0 (64 as metabs), Levodopa: <1%
- Biological half-life
- 1.5 · Benserazide: 1.5 / Increased, Levodopa: 1.5 / Increased by 25%
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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