8-Hydroxycarteolol

HCID 124688

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Basic information

CAS: 59826-22-1
Standard SMILES: CC(C)(C)NCC(O)COc1ccc(O)c2c1CCC(=O)N2
InChIKey: TVZJLAKRXHGVOK-UHFFFAOYSA-N
Molecular formula: C16H24N2O4
Average molar mass: 308.37 g/mol
Monoisotopic mass: 308.17360725

Overview

8-Hydroxycarteolol is a member of quinolines.

Names & identifiers

Preferred name: 8-Hydroxycarteolol
IUPAC: 5-[3-(tert-butylamino)-2-hydroxypropoxy]-8-hydroxy-3,4-dihydro-1H-quinolin-2-one
English name: 8-hydroxycarteolol
Molecular formula: C16H24N2O4
Molecular weight: 308.37

Names & synonyms

8-Hydroxycarteolol59826-22-1RefChem:1071605-[3-(tert-butylamino)-2-hydroxypropoxy]-8-hydroxy-3,4-dihydro-1H-quinolin-2-oneHYDROXYCARTEOLOLSCHEMBL11379793SCHEMBL31461066DTXSID50975219CHEBI:192312TVZJLAKRXHGVOK-UHFFFAOYSA-NQ170814235-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydroquinoline-2,8-diol

Show more names

Carteolol Hydrochloride Impurity 105-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-8-hydroxyquinolin-2(1H)-one2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-8-hydroxy-

8-hydroxy-5-(3-t-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyril2(1H)-Quinolinone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-8-hydroxy-

Database identifiers

CAS: 59826-22-1
PubChem CID: 124688
DTXSID: DTXSID50975219
ChEBI: CHEBI:192312
Nikkaji: J385.392F

Properties

Computed structural properties

XLogP: 0.6
Topological polar surface area: 90.8 Å²
Hydrogen bond donors: 4
Hydrogen bond acceptors: 5
Rotatable bonds: 6
Heavy atoms: 22
Formal charge: 0
Complexity: 383

Physicochemical properties

solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

Chemistry & industry

Pharmacology

Tissue LocationsKidney

Cellular LocationsCytoplasm

Applications

Uses8-Hydroxycarteolol Hydrochloride is a derivative of 8-Hydroxycarteolol (H926030) which is a high affinity b-adrenoceptor antagonist and a metabolite of Carteolol.