676-58-4[CH3-].[Cl-].[Mg+2]RQNMYNYHBQQZSP-UHFFFAOYSA-MMethylmagnesium chloride is an alkylmagnesium halide and a one-carbon compound.
676-58-4DTXSID7052365CHEBI:51492Wet Solid
In 3 M Tetrahydrofuran solution: Brown liquid with an odor of ether; [MSDSonline]
Moisture sensitive
... May react violently with water. /Methyl magnesium bromide in ethyl ether/
Danger
H225 (36.5%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P222, P223, P231, P231+P232, P233, P240, P241, P242, P243, P260, P264, P264+P265, P280, P301+P330+P331, P302+P335+P334, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P402+P404, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 263 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Chemical: Magnesium, chloromethyl-
Magnesium, chloromethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Magnesium, chloromethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Methylmagnesium chloride (EC: 211-629-7)
Magnesium, chloromethyl-: Does not have an individual approval but may be used under an appropriate group standard
A dangerous fire and explosion risk; [Hawley] Apart from their instability in air and their caustic basic properties, organomagnesium compounds and the precipitated inorganic magnesium salts produced during their use display no pronounced toxicity or side effects of environmental concern. [Ullmann] Reacts violently with water producing highly flammable gases; May form explosive peroxides; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]
Used as alkylating agent in organic synthesis and as a Grignard reagent; Also used to make tetramethyllead, styrallyl alcohol, and pharmaceuticals; [HSDB]
Alkylating agent in organic synthesis; grignard reagent
CHEM INT FOR MFR OF TETRAMETHYLLEAD
CHEM INT FOR MFR OF ALCOHOLS, EG, STYRALLYL ALCOHOL
CHEM INT FOR PHARMACEUTICALS, EG, STEROIDS
(1979) No Data
(1981) No Data
(1979) No Data
(1981) No Data
2023: <75,000 lb
(1977) AT LEAST 4.58X10+7 GRAMS
(1981) PROBABLY GREATER THAN 2.27X10+6 GRAMS
All Other Basic Organic Chemical Manufacturing
Magnesium, chloromethyl-: ACTIVE
UsesMethylmagnesium chloride is used as a Grignard reagent and an alkylating agent in organic synthesis.
reaction of methyl chloride and magnesium in anhydrous diethyl ether, usually in the presence of an initiator.
No reaction records under the current filter.
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/GUIDE 138: SUBSTANCES - WATER-REACTIVE (EMITTING FLAMMABLE GASES)/ Fire or Explosion: Produce flammable gases on contact with water. May ignite on contact with water or moist air. Some react vigorously or explosively on contact with water. May be ignited by heat, sparks or flames. May re-ignite after fire is extinguished. Some are transported in highly flammable liquids. Runoff may create fire or explosion hazard. /Organometallic substance, liquid, water-reactive, flammable/
/GUIDE 138: SUBSTANCES - WATER-REACTIVE (EMITTING FLAMMABLE GASES)/ Health: Inhalation or contact with vapors, substance, or decomposition products may cause severe injury or death. May produce corrosive solutions on contact with water. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control may cause pollution. /Organometallic substance, liquid, water-reactive, flammable/
/GUIDE 138: SUBSTANCES - WATER-REACTIVE (EMITTING FLAMMABLE GASES)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meter (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate the area before entry. /Organometallic substance, liquid, water-reactive, flammable/
/GUIDE 138: SUBSTANCES - WATER-REACTIVE (EMITTING FLAMMABLE GASES)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Organometallic substance, liquid, water-reactive, flammable/
For more DOT Emergency Guidelines (Complete) data for METHYLMAGNESIUM CHLORIDE (8 total), please visit the HSDB record page.
UN 3053; Magnesium alkyls
IMO 4.2; Magnesium alkyls
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
1.2 [mg/m3]
13 [mg/m3]
79 [mg/m3]
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . /Magnesium and Related Compounds/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in severe respiratory distress. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Magnesium and Related Compounds/
DefinitionChEBI: Methylmagnesium chloride is an alkylmagnesium halide and a one-carbon compound. available as a solutionin tetrahydrofuran.