Basic information
- CAS
678-26-2- Standard SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F- InChIKey
NJCBUSHGCBERSK-UHFFFAOYSA-N- Molecular formula
- C5F12
- Average molar mass
- 288.03 g/mol
- Monoisotopic mass
- 287.9808379
Names & identifiers
- Preferred name
- Perfluoropentane
- IUPAC
- 1,1,1,2,2,3,3,4,4,5,5,5-dodecafluoropentane
- English name
- Perfluoro-n-pentane
- Molecular formula
- C5F12
- Molecular weight
- 288.03
Names & synonyms
Show more names
Database identifiers
- CAS
678-26-2- PubChem CID
- 12675
- DTXSID
DTXSID3046613- ChEMBL
CHEMBL1899801- ChEBI
CHEBI:39428- UNII
- 483AU1Y5CZ
- EC Number
- 211-647-5
- Nikkaji
- J95.348B
Properties
Computed structural properties
- XLogP
- 4.5
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 2
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 250
Experimental & physicochemical properties
Physicochemical properties
- Melting point
- -120 °C · -120°C
- Boiling point
- 29 °C · 29°C
- Density
- 1 · 1,664 g/cm3
- refractive index
- 1.2412 · 1.2412
- Flash point
- 29 °C · 29°C
- solubility
- Benzene (Soluble), Ethyl Acetate (Soluble), Methanol (Soluble)
- form
- liquid
- color
- colorless
- BRN
- 1712388 · 1712388
- Henry's Law Constant
- 4.6 · 4.6×10-8 mol/(m3Pa) at 25℃, Brockbank (2013)
- Stability
- store cold
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 483 AU1Y5CZ · 483AU1Y5CZ
- ATC code
- 8 DA03 · V08DA03
- EPA Substance Registry System
- Perfluoropentane (678-26-2)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 280 · P280-P271
- Hazard Codes
- F,Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 9 · 9-23
- RIDADR
- 2810 · 2810
- RTECS
- 9890000 · RZ9890000
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HazardClass
- 6.1 · 6.1(b)
- PackingGroup
- III
- HS Code
- 2903493090 · 2903493090
- Toxicity
- 50 inhalation · LC50 inhalation in rat: 120gm/m3
Safety & regulation
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Toxicology
Regulatory information
Safety data
- tsca
- TSCA listed
- rtecs
- RZ9890000
- ridadr
- 2810
- hs_code
- 2903493090
- Toxicity
- LC50 inhalation in rat: 120gm/m3
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- F,Xi
- hazard_note
- Irritant
- safety_code
- 9-23
- hazard_class
- 6.1(b)
- packing_group
- III
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P280-P271
Chemistry & industry
Pharmacology
ATC Code
V - Various;V08 - Contrast media;V08D - Ultrasound contrast media;V08DA - Ultrasound contrast media;V08DA03 - Perflenapent
QV - Various;QV08 - Contrast media;QV08D - Ultrasound contrast media;QV08DA - Ultrasound contrast media;QV08DA03 - Perflenapent
Uses & manufacturing
Uses
Inert expander of tissue spaces, liquid at room temperature, but gaseous at body temperatures; used in experimental eye surgery. [ChemIDplus]
non-polymer PFAS -> Semiconductor Industry -> Etching the SiO2 coating of the semiconductor device;non-polymer PFAS -> Cleaning compositions -> Cleaning compositions for metal surfaces;non-polymer PFAS -> Tracing and tagging -> Tracing and tagging applications;non-polymer PFAS -> Energy Sector -> Organic Rankine engines;non-polymer PFAS -> Coatings, Paints and Varnishes -> Coatings for food contact materials others than paper;non-polymer PFAS -> Refrigerant systems -> Refrigerants;non-polymer PFAS -> Particle Physics -> The Delphi detector at CERN
• Refrigerant [Ref: https://www.ashrae.org/technical-resources/standards-and-guidelines/ashrae-refrigerant-designations];• Cleaning composition for metal surfaces [Ref: CAS2019 (US5750488)];• Used for tracing and trapping [Ref: http://www.f2chemicals.com/full_range.html];• Use in organic Rankine engine [Ref: http://www.f2chemicals.com/full_range.html];• Coating composition for food contact materials/cookware [Ref: CAS2019 (CN109370426)];• Plasma etching [Ref: Coburn, J. W. 1982. Plasma-Assisted Etching. Plasma Chemistry and Plasma Processing, 2 (1).]
Applications
UsesDiagnostic aid. [Note—The trademark EchoGen Emulsion has been selected for the mixture of Perflenapent and Perflisopent in a ratio of 85:15, respectively.
UsesPerfluoro-n-pentane is used in method for producing bubble formulation for theranostics.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers48 total
Additional notes
DefinitionChEBI: Perfluoropentane is a fluorocarbon that is pentane in which all of the hydrogens have been replaced by fluorines. It has a role as a radioopaque medium and an ultrasound contrast agent. It is a fluoroalkane and a fluorocarbon. It derives from a hydride of a pentane.
Related reactions
Compound notes
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