CAS 78756-03-3 Ro 14-7437 (HCID 127597)

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Basic information

CAS: 78756-03-3
Standard SMILES: CCOC(=O)c1ncn2c1CN(C)C(=O)c1ccccc1-2
InChIKey: HNGRWUCKESPKRC-UHFFFAOYSA-N
Molecular formula: C15H15N3O3
Average molar mass: 285.3 g/mol
Monoisotopic mass: 285.11134134

Overview

benzodiazepine antag; no other info available 8/16/83

Names & identifiers

Preferred name: Ro 14-7437
IUPAC: ethyl 5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
English name: Ro 14-7437
Molecular formula: C15H15N3O3
Molecular weight: 285.3

Names & synonyms

78756-03-3Ro 14-74374H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl esterRo-14-7437PP61C9NWB0DESFLUORO FLUMAZENILRefChem:930812Flumazenil EP Impurity ERO-147437ethyl 5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylateethyl 5-methyl-6-oxo-5,6-dihydro-4h-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylateCHEMBL267665

Show more names

Ro 14 7437,Ro 147437Flumazenil impurity E (EP)Flumazenil Related Compound C (USP)Flumazenil Impurity 5(Flumazenil EP Impurity E)ethyl 5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzo...ethyl 5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester; Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate; Ro 14-7437; Imp. E (EP)ETHYL 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXYLATEETHYL 5-METHYL-6-OXO-5,6-DIHYDRO-4H-BENZO(F)IMIDAZO(1,5-A)(1,4)DIAZEPINE-3-CARBOXYLATEUNII-PP61C9NWB0orb1699509SCHEMBL7327790DTXSID10999991

Properties

Computed structural properties

XLogP: 0.9
Topological polar surface area: 64.4 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 4
Rotatable bonds: 3
Heavy atoms: 21
Formal charge: 0
Complexity: 428

Physicochemical properties

FDA UNII: 61 C9NWB0 · PP61C9NWB0

Chemistry & industry

Applications · 1 item

UsesEthyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate-d3 is an isotope labelled analog for Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate. Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate, is used in the biological studies and preparation of imidazobenzodiazepines as probes for diazepaminsensitive receptor pharmacophore.