Basic information
- CAS
105350-26-3- Standard SMILES
O=C(O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1- InChIKey
LMPZHLXYBWGGNT-UHFFFAOYSA-N- Molecular formula
- C23H18N2O3
- Average molar mass
- 370.4 g/mol
- Monoisotopic mass
- 370.13174244
Overview
2-[3-(2-quinolinylmethoxy)anilino]benzoic acid is a member of quinolines.
Names & identifiers
- Preferred name
- SR 2640
- IUPAC
- 2-[3-(quinolin-2-ylmethoxy)anilino]benzoic acid
- English name
- 2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE
- Molecular formula
- C23H18N2O3
- Molecular weight
- 370.4
Names & synonyms
105350-26-3SR 2640SR-2640SR26402-((3-(Quinolin-2-ylmethoxy)phenyl)amino)benzoic acid2-{[3-(quinolin-2-ylmethoxy)phenyl]amino}benzoic acidRefChem:185179Benzoic acid, 2-[[3-(2-quinolinylmethoxy)phenyl]amino]-2-[3-(quinolin-2-ylmethoxy)anilino]benzoic acidCHEMBL18132Benzoic acid, 2-((3-(2-quinolinylmethoxy)phenyl)amino)-SR-01000076219
Show more names
SR2640HClSR 2640 HYDROCHLORIDE2-[[3-[(Quinolin-2-yl)methoxy]phenyl]amino]benzoic acid2-[3-(2-Quinolylmethoxy)phenylamino]benzoic acid hydrochloride2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE2-((3-(Quinolin-2-ylMethoxy)phenyl)aMino)benzoic acid hydrochloride
Tocris-1804SR2640 hydrochloride?Lopac-S-76902-(3-(2-Quinolylmethoxy)phenylamino)benzoic acidLopac0_001079MLS002153402SR 2640 HClcid_128355
Database identifiers
Properties
Computed structural properties
- XLogP
- 5.3
- Topological polar surface area
- 71.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 514
Experimental & physicochemical properties
Collision Cross Section183.07 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- Melting point
- 136 °C · >136°C (dec.)
- Boiling point
- 580.3 · 580.3±45.0 °C(Predicted)
- Density
- 1.322 · 1.322±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- solubility
- 50 mg/mL, · DMSO: 50 mg/mL, soluble
- form
- solid
- pka
- 3.67 · 3.67±0.36(Predicted)
- color
- yellow, powder with a tan cast
- Stability
- Hygroscopic
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 319 · H319-H335-H315
- Precautionary statements
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- 3
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Hazard statements
- H319-H335-H315
- Precautionary statements
- P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
UsesSR 2640 Hydrochloride is a useful intermediate. It is a potent, selective LTD4 /LTE4 receptor antagonist.
Suppliers24 total
上海微佳禾生物科技有限公司17502176150; 17502176150 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海尺水药物研究有限公司[email protected] 13564957716 · [email protected]
武汉艾瑞尔化学科技有限公司18986259541 18986259541 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
赛纳斯特化学（欢迎点击联系）021-60343070
武汉凯美克化学科技有限公司027-87342388 18086026008 · [email protected]
台州川旭医药科技有限公司[email protected] 15165038510 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
武汉壹加壹生物科技有限公司027-027-16602739303 16602739303 · [email protected]
上海楼岚生物科技有限公司021-52996696，15000506266 15000506266
成都佶安特生物医药科技有限公司请加QQ询价！ · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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