Basic information
- CAS
103788-05-2- Standard SMILES
Cc1oc(-c2ccccc2)nc1C(O)COc1ccc(CC2SC(=O)NC2=O)cc1- InChIKey
YVQKIDLSVHRBGZ-UHFFFAOYSA-N- Molecular formula
- C22H20N2O5S
- Average molar mass
- 424.5 g/mol
Names & identifiers
- Preferred name
- AD 5075
- IUPAC
- 5-[[4-[2-hydroxy-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
- English name
- AD-5075
- Molecular formula
- C22H20N2O5S
- Molecular weight
- 424.4696
Names & synonyms
103788-05-2AD-5075AD50755-[[4-[2-hydroxy-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dioneAD 50752,4-Thiazolidinedione, 5-((4-(2-hydroxy-2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy)phenyl)methyl)-5-((4-(2-hydroxy-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)methyl)-1,3-thiazolidine-2,4-dioneRefChem:9151302,4-Thiazolidinedione,5-[[4-[2-hydroxy-2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]-5-(4-(2-(5-Methyl-2-phenyl-4-oxazolyl)-2-hydroxyethoxy)benzyl)-2,4-thiazolidinedioneYVQKIDLSVHRBGZ-UHFFFAOYSA-N[3H]AD5075
Show more names
[3H]-AD5075CHEMBL88496SCHEMBL131888GTPL2701GTPL2702orb1698750DTXSID00908597EX-A11923
Database identifiers
- CAS
103788-05-2- PubChem CID
- 128440
- DTXSID
DTXSID00908597- ChEMBL
CHEMBL88496- Nikkaji
- J460.685J
Properties
Computed structural properties
- XLogP
- 3.4
- Topological polar surface area
- 127 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 7
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 606
Chemistry & industry
Applications
UsesAD-5075 is an orally active insulin sensitizer. AD-5075 mediates its antidiabetic activity by binding to PPARγ and thereby generating an active conformation of the receptor[1].
Suppliers3 total
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Related reactions
1 records
Compound notes
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