Tea, ext.
Green Tea Extract · CAMELLIA SINENSIS LEAF EXTRACT · Black tea extract · TEA POLYPHENOLS · Green Tea Extract Powder · Tea, ext. · tea leaf absolute · Theaflavinum
Identifiers & Physical Properties
| CAS No. | 84650-60-2 |
|---|---|
| Molecular formula | C22H18O11 |
| Average molar mass | 458.4 g/mol |
| Monoisotopic mass | 458.0849114 g/mol |
| SMILES | O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 |
| InChIKey | WMBWREPUVVBILR-UHFFFAOYSA-N |
| PubChem CID | 1287 |
| ChEMBL | CHEMBL311663 |
| ChEBI | CHEBI:182308 |
| EC No. | 283-519-7 |
| DTXSID | DTXSID00859570 |
Chemical & Physical Properties
| XLogP | 1.2 |
|---|---|
| Topological polar surface area | 197 |
| Hydrogen bond donors | 8 |
| Hydrogen bond acceptors | 11 |
| Rotatable bonds | 4 |
| Heavy atoms | 33 |
| Formal charge | 0 |
| Complexity | 667 |
| Cosmetics | Skin conditioningTonicAstringent |
| Food additives | FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food |
| Storage conditions | -20°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Physical state | Solid |
| Color | Light Orange |
| Odor | at 100.00 %. tea |
| Odor type | herbal |
| Major applications | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions | PERFUMINGBLEACHINGORAL CARETONICUV ABSORBERASTRINGENTANTIMICROBIALFRAGRANCEEXFOLIATINGANTI-SEBUMSKIN CONDITIONING - EMOLLIENTSKIN PROTECTINGHUMECTANTANTIOXIDANTSKIN CONDITIONING |
| Cosmetic Ingredient Review (CIR) | Tea polyphenol (84650-60-2) |
| Substances Added to Food (formerly EAFUS) | TEA EXTRACT (THEA SINENSIS L.) |
| NCI Dictionary of Cancer Terms | green tea extract |
| NCI Drug Dictionary | green tea extract |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
| GHS pictogram | GHS02,GHS07 |
| Signal word | Warning |
| GHS hazard statements | H225-H319-H226 |
| GHS precautionary statements | P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501-P264-P280-P305+P351+P338-P337+P313P |
| Water hazard class (WGK) | 3 |
| Customs code | 2101200040 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| GHS classification | This chemical does not meet GHS hazard criteria for 18.9% (313 of 1658) of reports.DangerH225 (77.8%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1658 reports by companies from 15 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatory information | Tea, ext.: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 2 (77.8%) |
| Water hazard class (WGK) | 3 |
| Customs code | 2101200040 |
| Signal word | Warning |
| GHS pictogram | GHS02,GHS07 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H225-H319-H226 |
| GHS precautionary statements | P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501-P264-P280-P305+P351+P338-P337+P313P |
Applications & Uses
Description
The phenolic compounds in tea (tea polyphenols) are also known as catechins. In green tea, the four major catechins are (-)-epigallocatechin-3-gallate (EGCG) and its derivatives including (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECG), and (-)-epicatechin (EC). EGCG takes around 50-80% of the total catechin in green tea and it has been shown to be responsible for much of the health promoting ability of green tea.Tea polyphenols exhibit anti-carcinogenic, anti-oxidative, anti-allergic, antiviral, anti-hypertensive, anti-atherosclerosis, anti-cardiovascular disease and anti-hypercholesterolemic activities. EGCG has shown to inhibit hepatitis C virus entry and carcinogenesis. Studies suggest that tea polyphenols may help treat health conditions including atherosclerosis, high cholesterol, and cancers including bladder cancer, breast cancer, ovarian cancer, colorectal cancer, esophageal cancer, lung cancer, pancreatic cancer, prostate cancer, skin cancer, and stomach cancer. Tea polyphenols could be helpful in treating inflammatory diseases.
Uses
green tea extract (Camellia sinensis L.) is a powerful anti-oxidant because of its catechin content, it is also known to be an antibacterial, anti-inflammatory, and a stimulant. In clinical studies, green tea demonstrates an ability to prevent or at least postpone the onset of such illnesses as cancer and heart disease. This is attributed to the catechin component’s ability to penetrate into a cell, thereby protecting the cell from free radicals and associated damage. Because of its anti-oxidant properties, green tea is usually incorporated into anti-aging formulations. When applied topically, it can also reduce skin swelling. In addition, it can be found in sunscreens, given its ability to extend the product’s SPF. The extract and its associated catechins can be obtained from both the plant and its dried leaves. other constituents of green tea include caffeine and phenolic acids.