Basic information
- CAS
1421747-19-4- Standard SMILES
C[C@H]1CN(O)CCc2ccc(Cl)cc21- InChIKey
OBKJFJJRKLOMQV-QMMMGPOBSA-N- Molecular formula
- C11H14ClNO
- Average molar mass
- 211.69 g/mol
- Monoisotopic mass
- 211.0763918
Names & identifiers
- Preferred name
- Lorcaserin N-hydroxy
- IUPAC
- (5R)-7-chloro-3-hydroxy-5-methyl-1,2,4,5-tetrahydro-3-benzazepine
- English name
- Lorcaserin N-Hydroxy Impurity
- Molecular formula
- C11H14ClNO
- Molecular weight
- 211.69
Names & synonyms
1421747-19-4Lorcaserin N-hydroxyLorcaserin metabolite M37ZH44Z86BJ1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-3-hydroxy-1-methyl-, (1R)-RefChem:201503N-Hydroxy LorcaserinN-Hydroxylorcaserin(5R)-7-chloro-3-hydroxy-5-methyl-1,2,4,5-tetrahydro-3-benzazepine(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ol(1R)-8-Chloro-2,3,4,5-tetrahydro-3-hydroxy-1-methyl-1H-3-benzazepineUNII-7ZH44Z86BJ
Show more names
Lorcaserin N-OxideLorcaserin N-Hydroxy ImpurityLorcaserin Impurity 12 (Lorcaserin N-Oxide)
Database identifiers
- CAS
1421747-19-4- PubChem CID
- 129011985
- UNII
- 7ZH44Z86BJ
Properties
Computed structural properties
- XLogP
- 2.7
- Topological polar surface area
- 23.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 200
Physicochemical properties
- Boiling point
- 332 · 332.0±42.0 °C(Predicted)
- Density
- 1.216 · 1.216±0.06 g/cm3(Predicted)
- storage temp.
- 2 · Storage temp. 2-8°C
- solubility
- Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.36 · 13.36±0.40(Predicted)
- color
- White to Light Beige
- Stability
- Hygroscopic
- FDA UNII
- 7 ZH44Z86BJ · 7ZH44Z86BJ
Chemistry & industry
Pharmacology
Tissue LocationsKidney
Cellular LocationsCytoplasm
Applications
UsesN-Hydroxy Lorcaserin is a metabolite of Lorcaserin (L469890, HCl); a novel selective 5-HT2C-receptor agonist for the treatment of obesity.
Suppliers7 total
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
sgtlifesciences pvt ltd+91-8790379245 · [email protected]
TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
上海甄准生物科技有限公司18019219489 18901678489 · [email protected]
卡托研究化学公司+86-020-81960175-877 4000-868-328;4000-868-328 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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