Basic information
- CAS
186521-88-0- Standard SMILES
CC(CO)CC(N)C1(c2ccc(Cl)cc2)CCC1.Cl- InChIKey
HXIZALIKJURKFS-UHFFFAOYSA-N- Molecular formula
- C15H23Cl2NO
- Average molar mass
- 304.3 g/mol
- Monoisotopic mass
- 303.1156697
Names & identifiers
- Preferred name
- (N,N-didemethyl) 1-Hydroxy Sibutramine Hydrochloride
- IUPAC
- 4-amino-4-[1-(4-chlorophenyl)cyclobutyl]-2-methylbutan-1-ol;hydrochloride
- English name
- (N,N-dideMethyl) 1-Hydroxy SibutraMine Hydrocholride
- Molecular formula
- C15H23Cl2NO
- Molecular weight
- 304.26
Names & synonyms
186521-88-0(N,N-didemethyl) 1-Hydroxy Sibutramine Hydrocholride(N,N-didemethyl) 1-Hydroxy Sibutramine Hydrochloride4-amino-4-[1-(4-chlorophenyl)cyclobutyl]-2-methylbutan-1-ol;hydrochlorided-?Amino-?1-?(4-?chlorophenyl)?-?ss-?methylcyclobutanebutanol HydrocholrideV9AFR5ELG4delta-Amino-1-(4-chlorophenyl)-beta-methylcyclobutanebutanol Hydrocholride(N,N-Didemethyl)-1-Hydroxy-Sibutramine HClN,N-Didesmethyl 1-Hydroxy Sibutramine (Mixture of Diastereomers)delta-Amino-1-(4-chlorophenyl)-beta-methylcyclobutanebutanol hydrochlorideCyclobutanebutanol, delta-amino-1-(4-chlorophenyl)-beta-methyl-, hydrochlorideCyclobutanebutanol, delta-amino-1-(4-chlorophenyl)-beta-methyl-, hydrochloride (1:1)
Show more names
1-Hydroxy didesmethyl SibutramineSertraline Impurity 1 Monomer（Sertraline EP Impurity A Monomer）
Properties
Computed structural properties
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 5
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 259
Physicochemical properties
- Melting point
- 86 °C · >86°C (dec.)
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Sparingly)
- form
- Solid
- color
- White to Off-White
- Stability
- Hygroscopic
Chemistry & industry
Applications
UsesDe(N,N-dimethyl) 1-Hydroxy Sibutramine Hydrocholride is an intermediate in the synthesis of De(N,N,3-trimethyl) Sibutramine Hydrocholride (D298380), an analogue of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
Suppliers9 total
艾吉析科技（上海）有限公司17717235263 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
Cato Research Chemicals Inc.020-81960175 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
sgtlifesciences pvt ltd+91-8790379245 · [email protected]
BOC Sciences16314854226 · [email protected]
深圳市祥根生物医药有限公司0755-28967200 13631290199 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…