Aminoacylase
Basic information
- CAS
9012-37-7- Standard SMILES
[HH].[HH].[HH]- InChIKey
ULGJWNIHLSLQPZ-UHFFFAOYSA-N- Molecular formula
- H6
- Average molar mass
- 6.048 g/mol
- Monoisotopic mass
- 6.04695019
Names & identifiers
- Preferred name
- Aminoacylase
- IUPAC
- molecular hydrogen
- English name
- Aminoacylase
- Molecular formula
- C30H34Cl2N4O
- Molecular weight
- 537.52316
Names & synonyms
AminoacylaseBenzamidaseHippuraseHistozymeL-AminoacylaseDehydropeptidase IIAmino acid deacylaseL-Amino acid acylaseRefChem:557532DTXSID1093830EINECS 232-732-3E.C. 3.5.1.14
Show more names
ACYLASE IhippuricaseACYLASE 1acyclase IEC 3.5.1.14
232-732-39012-37-7AcylaseMFCD00081285PD078400SY008827
Database identifiers
- CAS
9012-37-7- PubChem CID
- 129012201
- EC Number
- 232-732-3
Properties
Computed structural properties
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 0
- Heavy atoms
- 0
- Formal charge
- 0
- Complexity
- 0
Physicochemical properties
- storage temp.
- 2 · 2-8°C
- form
- salt-free, lyophilized powder
- color
- yellow-brown
- Specific Activity
- 300 · 300-1,500units/mg protein
- InChIKey
- ULGJWNIHLSLQPZ-UHFFFAOYSA-N
- SMILES
- C(NCCC1C2=C(NC=1)C=CC=C2)(=O)CCCCCCNC1C2CCCCC=2N=C2C=1C(Cl)=CC(Cl)=C2
- EWG's Food Scores
- 1 · 1
- EPA Substance Registry System
- Aminoacylase (9012-37-7)
- UNSPSC Code
- 12352204 · 12352204
- NACRES
- 54 · NA.54
- Symbol(GHS)
- 7 · GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- 315 · H315-H319-H334-H335
- Precautionary statements
- 261 · P261-P264-P271-P302+P352-P304+P340+P312-P305+P351+P338
- target organs
- Respiratory system
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H315 (88.9%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 45 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).
Aminoacylase: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (88.9%)
Safety data
- F
- 3-10-21
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- BF4890000
- hs_code
- 35079090
- risk_code
- 36/37/38-42
- Signal word
- Danger
- Symbol(GHS)
- GHS07,GHS08
- hazard_code
- Xn
- safety_code
- 22-24/25-36/37-26-24
- Storage Class
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationAminoacylase: INACTIVE
Applications
DescriptionAminoacylase-1 (EC 3.5.1.14) is a homodimeric zinc-binding metalloenzyme. A cytosolic enzyme with a wide range of tissue expression, it cleaves acylated L-amino acids (except L-aspartate) into L-amino acids and an acyl group. L-aspartate derivatives are cleaved by aminoacylase-2 (aspartoacylase). Aminoacylase-1 is the most abundant of the aminoacylases, a class of enzymes involved in hydrolysis of N-acetylated proteins.
UsesAcylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .
General DescriptionAcylase I belongs to the aminoacylase family of enzymes.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…