2-(2-(3-Iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole
Basic information
- CAS
106050-84-4- Standard SMILES
CN1CCN(c2ccc3nc(-c4ccc5nc(-c6ccc(O)c(I)c6)[nH]c5c4)[nH]c3c2)CC1- InChIKey
ZGUNSONXLSTYPT-UHFFFAOYSA-N- Molecular formula
- C25H23IN6O
- Average molar mass
- 550.4 g/mol
- Monoisotopic mass
- 550.09781
Overview
structure given in first source
Names & identifiers
- Preferred name
- 2-(2-(3-Iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole
- IUPAC
- 2-iodo-4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol
- English name
- 2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole
- Molecular formula
- C25H23IN6O
- Molecular weight
- 550.39
Names & synonyms
106050-84-42-(2-(3-Iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazoleRefChem:839682-iodo-4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol2-Iodo-4-(5-(4-methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenolorb1706355SCHEMBL10070224AKOS040744080CS-1318DA-74247HY-15630PD118611
Show more names
monoiodoHoechst 33258Hoechst 33342 analog 2Phenol, 2-iodo-4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]- (9CI)
T19009Phenol, 2-iodo-4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)-
Database identifiers
- CAS
106050-84-4- PubChem CID
- 129169
Properties
Computed structural properties
- XLogP
- 4.6
- Topological polar surface area
- 84.1 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 677
Physicochemical properties
- Boiling point
- 747.5 · 747.5±70.0 °C(Predicted)
- Density
- 1.642 · 1.642±0.06 g/cm3(Predicted)
- solubility
- 57 mg/mL · DMSO : ≥ 57 mg/mL (103.56 mM);
- form
- Powder
- pka
- 7.82 · 7.82±0.20(Predicted)
- color
- Pale purple to khaki
- Appearance
- Solid Powder
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
DescriptionHoechst 33342 analog 2 is an analog of Hoechst 33342 that can be used for staining DNA.
UsesHoechst 33342 analog 2 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…